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Gastrointestinal Involvement in Extra-Digestive Disease: Which Is the Role of Fecal Calprotectin?

Journal

MEDICINA-LITHUANIA
Volume 58, Issue 10, Pages -

Publisher

MDPI
DOI: 10.3390/medicina58101384

Keywords

fecal calprotectin; psoriasis; behcet's disease; atopic dermatitis; parkinson's disease; alzheimer's disease; COVID-19

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Fecal calprotectin is a sensitive marker of gastrointestinal inflammation, and it has clinical utility in intestinal and extraintestinal diseases. Recent evidence suggests its association with dermatological, rheumatic, and neurological diseases, as well as its role in SARS-CoV-2 infection.
Fecal calprotectin (FC) is a very sensitive marker of inflammation of the gastrointestinal tract. Its clinical utility can be appreciated in both intestinal and extraintestinal diseases. Recent evidence suggests a link between intestinal inflammation and dermatological, rheumatic and neurological diseases. This review focuses on the role of FC in non-gastrointestinal disease, such as rheumatic, dermatologic, neurologic and last but not least SARS-CoV-2 infection.

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