4.7 Article

Chemical constitutes and anti-obesity potential of seedlings of purple-leafed rice in high-fat diet induced obese mice

Journal

FOOD & FUNCTION
Volume 13, Issue 23, Pages 12426-12435

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2fo02374a

Keywords

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Funding

  1. Fundamental Research Funds for the Central Universities
  2. [2662020SPPY004]
  3. [2662021SPPY002]

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Purple leafed rice (SPLR) seedlings, characterized by high amounts of anthocyanins and polyphenols, have shown potential in preventing obesity and related complications by alleviating obesity and suppressing pro-inflammatory cytokines and macrophage infiltration.
The seedlings of purple leafed rice (SPLR) are characterized by high contents of anthocyanins and various polyphenols, whose total anthocyanin content can reach 15.16 mg g(-1), indicating that SPLR may have many bioactivities. Therefore, in order to evaluate the anti-obesity potential value of SPLR, the nutrient components were first identified, and the anti-obesity effect of SPLR was evaluated with a high-fat diet (HFD) induced obese mouse model for 12 weeks. The results demonstrated that SPLR supplementation could alleviate HFD-induced obesity and suppress pro-inflammatory cytokine production and macrophage infiltration in epididymal white adipose tissue of HFD-induced obese mice. The findings indicated that supplementation with SPLR may contribute to preventing obesity and related complications.

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