Journal
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO
Volume 64, Issue -, Pages -Publisher
INST MEDICINA TROPICAL SAO PAULO
DOI: 10.1590/S1678-9946202264067
Keywords
Renal dialysis; Centrifuge; Bacillus cereus group; Biofilm
Categories
Funding
- CAPES
- Brazilian Coordination for Improvement of Higher Education Personnel [001]
- CNPq (the Brazilian Council for Scientific and Technological Development)
Ask authors/readers for more resources
This study demonstrates the persistence of B. cereus in the hemodialysis system, highlighting its ability to form biofilms, produce virulence factors, and exhibit resistance to antimicrobial drugs.
In this study, B. cereus was detected in dialysis fluids within international parameters (ultrapure - maximum limit of 0.1 CFU/mL for heterotrophic bacteria count) by analyzing the pellet obtained through the centrifugation method. We also investigated the ability of the B. cereus isolate to form a biofilm at different temperatures, the production of virulence factors, and the susceptibility to commercial antimicrobial agents. This study demonstrated a high ability of B. cereus to persist in the hemodialysis system, which can be explained by its broad ability to produce a biofilm at 25 degrees C, its relevant production of virulence factors, such as beta-hemolysin, lecithinase and cereulide, and its important resistance pattern to antimicrobial drugs. In conclusion, these new findings expand the understanding that this microorganism should not be neglected and new methods for tracking it should be considered.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available