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Role and Cellular Source of Nicotinamide Adenine Dinucleotide Phosphate Oxidase in Hepatic Fibrosis
Samuele De Minicis et al.
HEPATOLOGY (2010)
Histone Deacetylase Inhibition Suppresses the Transforming Growth Factor β1-Induced Epithelial-to-Mesenchymal Transition in Hepatocytes
Aki Kaimori et al.
HEPATOLOGY (2010)
Valproic Acid Administration for Hepatic Fibrosis: A Balance Between Antifibrotic Efficacy and Hepatotoxicity
Yoshihiro Ikura et al.
HEPATOLOGY (2010)
Attenuation of warm ischemia-reperfusion injury in the liver by bucillamine through decreased neutrophil activation and Bax/Bcl-2 modulation
Sameer P. Junnarkar et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2010)
Preservation of basal AcSDKP attenuates carbon tetrachloride-induced fibrosis in the rat liver
Yuan-Wen Chen et al.
JOURNAL OF HEPATOLOGY (2010)
New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis
Yan Wang et al.
JOURNAL OF HEPATOLOGY (2010)
Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells
Jonel Trebicka et al.
JOURNAL OF HEPATOLOGY (2010)
Danshen extract 15,16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways
Qiong Liu et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis
Christoph Dorn et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2010)
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
Vivian Barry-Hamilton et al.
NATURE MEDICINE (2010)
Cultivation and Breeding of Chinese Medicinal Plants in Germany
Heidi Heuberger et al.
PLANTA MEDICA (2010)
Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice
George L. Tipoe et al.
TOXICOLOGY (2010)
Colchicine reduces procollagen III and increases pseudocholinesterase in chronic liver disease
Sergio Muntoni et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2010)
Protective effect of Livactine against CCl4 and paracetamol induced hepatotoxicity in adult Wistar rats
Candasamy Mayuren et al.
NORTH AMERICAN JOURNAL OF MEDICAL SCIENCES (2010)
Epigallocatechin-3-Gallate, a Histone Acetyltransferase Inhibitor, Inhibits EBV-Induced B Lymphocyte Transformation via Suppression of ReIA Acetylation
Kyung-Chul Choi et al.
CANCER RESEARCH (2009)
Tyrosine-phosphorylation: thirty years and counting
Tony Hunter
CURRENT OPINION IN CELL BIOLOGY (2009)
N-acetylcysteine prevents carbon tetrachloride-induced liver cirrhosis: role of liver transforming growth factor-beta and oxidative stress
Marina Galicia-Moreno et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2009)
PDGFRα: a new therapeutic target in the treatment of hepatocellular carcinoma?
Abdul M. Oseini et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Kupffer Cells Mediate Leptin-Induced Liver Fibrosis
Jianhua Wang et al.
GASTROENTEROLOGY (2009)
Competitive Inhibition of Leptin Signaling Results in Amelioration of Liver Fibrosis Through Modulation of Stellate Cell Function
Eran Elinav et al.
HEPATOLOGY (2009)
Protective effects of astragaloside IV on porcine-serum-induced hepatic fibrosis in rats and in vitro effects on hepatic stellate cells
Hao Liu et al.
JOURNAL OF ETHNOPHARMACOLOGY (2009)
The Lysyl Oxidase Inhibitor, β-Aminopropionitrile, Diminishes the Metastatic Colonization Potential of Circulating Breast Cancer Cells
Alla Bondareva et al.
PLOS ONE (2009)
Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice
Yue-Min Nan et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2009)
Liver fibrosis in mice induced by carbon tetrachloride and its reversion by luteolin
Robert Domitrovic et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)
Connective tissue growth factor hammerhead ribozyme attenuates human hepatic stellate cell function
Run-Ping Gao et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Effect of Fuzheng Huayu formula and its actions against liver fibrosis
Chenghai Liu et al.
Chinese Medicine (2009)
Potent antioxidant role of Pirfenidone in experimental cirrhosis
Adriana Salazar-Montes et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7
Yutaka Inagaki et al.
GASTROENTEROLOGY (2008)
Coagulation and fibrosis in chronic liver disease
V. Calvaruso et al.
GUT (2008)
Statins in liver disease: A molehill, an iceberg, or neither?
Curtis K. Argo et al.
HEPATOLOGY (2008)
Tetrandrine protects mice from concanavalin A-induced hepatitis through inhibiting NF-κB activation
Dechun Feng et al.
IMMUNOLOGY LETTERS (2008)
Effect of Unfiltered Coffee on Carbon Tetrachloride-Induced Liver Injury in Rats
Orhan Kursat Poyrazoglu et al.
INFLAMMATION (2008)
RNA interfering connective tissue growth factor prevents rat hepatic stellate cell activation and extracellular matrix production
Guangming Li et al.
JOURNAL OF GENE MEDICINE (2008)
Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats
Alejandra M. Camino et al.
JOURNAL OF GENE MEDICINE (2008)
Reduction of hepatocellular injury after common bile duct ligation using omega-3 fatty acids
Sang Lee et al.
JOURNAL OF PEDIATRIC SURGERY (2008)
Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats
J. H. Tsai et al.
JOURNAL OF VIRAL HEPATITIS (2008)
Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury
Erawan Borkham-Kamphorst et al.
LABORATORY INVESTIGATION (2008)
Disruption of connective tissue growth factor by short hairpin RNA inhibits collagen synthesis and extracellular matrix secretion in hepatic stellate cells
Zhu Yuhua et al.
LIVER INTERNATIONAL (2008)
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
Scott L. Friedman
PHYSIOLOGICAL REVIEWS (2008)
Down-regulation of transforming growth factor β1/activin receptor-like kinase 1 pathway gene expression by herbal compound 861 is related to deactivation of LX-2 cells
Li Li et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
Herbal compound 861 regulates the mRNA expression of collagen synthesis- and degradation-related genes in human hepatic stellate cells
Lin Wang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
Resveratrol prevents fibrosis, NF-kappa B activation and TGF-beta increases induced by chronic CCl4 treatment in rats
Enrique Chavez et al.
JOURNAL OF APPLIED TOXICOLOGY (2008)
Antiangiogenic treatment with Sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats
Snia Tugues et al.
HEPATOLOGY (2007)
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
Penelope C. Georges et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes
Olav A. Gressner et al.
JOURNAL OF HEPATOLOGY (2007)
Quercetin prevents oxidative stress in cirrhotic rats
Pavanato Maria Amalia et al.
DIGESTIVE DISEASES AND SCIENCES (2007)
Histone deacetylase inhibitors: Overview and perspectives
Milos Dokmanovic et al.
MOLECULAR CANCER RESEARCH (2007)
Results of European post-marketing surveillance of bosentan in pulmonary hypertension
M. Humbert et al.
EUROPEAN RESPIRATORY JOURNAL (2007)
Cyclic Arg-Gly-Asp peptide-labeled liposomes for targeting drug therapy of hepatic fibrosis in rats
Shi-Lin Du et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats
Kohji Kinoshita et al.
GUT (2007)
Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies
Stefanie Hemmann et al.
JOURNAL OF HEPATOLOGY (2007)
siRNA-mediated knockdown of connective tissue growth factor prevents N-nitrosodimethylamine-induced hepatic fibrosis in rats
J. George et al.
GENE THERAPY (2007)
Omega-3 fatty acids alleviate chemically induced acute hepatitis by suppression of cytokines
Christoph Schmoecker et al.
HEPATOLOGY (2007)
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats
Ying-Bin Hu et al.
JOURNAL OF GENE MEDICINE (2007)
Tetrandrine stimulates the apoptosis of hepatic stellate cells and ameliorates development of fibrosis in a thioacetamide rat model
Ming-Fu Yin et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2007)
Deficiency of tenascin-C attenuates liver fibrosis in immune-mediated chronic hepatitis in mice
A. El-Karef et al.
JOURNAL OF PATHOLOGY (2007)
Antioxidant properties of Bucillamine: Possible mode of action
Dalia Mazor et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice
Piotr Czochra et al.
JOURNAL OF HEPATOLOGY (2006)
Antiproliferative effect of salvianolic acid A on rat hepatic stellate cells
Yun-Lian Lin et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2006)
Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats
Guangming Li et al.
JOURNAL OF GENE MEDICINE (2006)
Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats
I. A. Leclercq et al.
GUT (2006)
Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligation
JL Xia et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Water-soluble extract of Salvia miltiorrhiza ameliorates carbon tetrachloride-mediated hepatic apoptosis in rats
Tzung-Yan Lee et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2006)
Discovery of 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide (GW788388):: A potent, selective, and orally active transforming growth factor-β type I receptor inhibitor
F Gellibert et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
NC Henderson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice
Martin Roderfeld et al.
FASEB JOURNAL (2006)
Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers
WI Hagens et al.
LIVER INTERNATIONAL (2006)
Osteopontin expression in normal and fibrotic liver.: Altered liver healing in. osteopontin-deficient mice
D Lorena et al.
JOURNAL OF HEPATOLOGY (2006)
Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets
A. M. Gressner et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2006)
Smad3 specific inhibitor, naringenin, decreases the expression of extracellular matrix induced by TGF-beta 1 in cultured rat hepatic stellate cells
XJ Liu et al.
PHARMACEUTICAL RESEARCH (2006)
N-Acetyl-L-cysteine suppresses TGF-β signaling at distinct molecular steps:: The biochemical and biological efficacy of a multifunctional, antifibrotic drug
SK Meurer et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Role of reactive oxygen species in zinc deficiency-induced hepatic stellate cell activation
A Kojima-Yuasa et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis
AM Zuurmond et al.
MATRIX BIOLOGY (2005)
The roles of leptin and adiponectin: A novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology
XK Ding et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Multicenter clinical study on Fuzhenghuayu capsule against liver fibrosis due to chronic hepatitis B
Ping Liu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2005)
Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats
R Bataller et al.
HEPATOLOGY (2005)
Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation
HL Liu et al.
ACTA PHARMACOLOGICA SINICA (2005)
Inhibition of TGF-β signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis
AC de Gouville et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
Colchicine treatment of alcoholic cirrhosis: A randomized, placebo-controlled clinical trial of patient survival
TR Morgan et al.
GASTROENTEROLOGY (2005)
Omega-3 fatty acid supplementation prevents hepatic steatosis in a murine model of nonalcoholic fatty liver disease
IPJ Alwayn et al.
PEDIATRIC RESEARCH (2005)
Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma
JS Campbell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria
BJ Chang et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Minoxidil, a K-ATP channel opener, accelerates DNA synthesis following partial hepatectomy in rats
K Yamasaki et al.
BIOFACTORS (2005)
Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice
H Okuyama et al.
JOURNAL OF HEPATOLOGY (2005)
Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet
K Kawaguchi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
PAR1 antagonism protects against experimental liver fibrosis.: Role of proteinase receptors in stellate cell activation
S Fiorucci et al.
HEPATOLOGY (2004)
Melatonin reduces dimethylnitrosamine-induced liver fibrosis in rats
V Tahan et al.
JOURNAL OF PINEAL RESEARCH (2004)
Effects and regulation of osteopontin in rat hepatic stellate cells
SH Lee et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells
JG Orr et al.
HEPATOLOGY (2004)
The flavonoid naringenin inhibits dimethylnitrosamine-induced liver damage in rats
MH Lee et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2004)
Dominant-negative soluble PDGF-β receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis
E Borkham-Kamphorst et al.
LABORATORY INVESTIGATION (2004)
A role for thrombin in liver fibrosis
JG Duplantier et al.
GUT (2004)
Down-regulation of connective tissue growth factor and type I collagen mRNA expression by connective tissue growth factor antisense oligonucleotide during experimental liver fibrosis
K Uchio et al.
WOUND REPAIR AND REGENERATION (2004)
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
JF Stevens et al.
PHYTOCHEMISTRY (2004)
Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats -: art. no. 29
M Arias et al.
BMC GASTROENTEROLOGY (2003)
Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis
CD Yu et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model
R Dekel et al.
DIGESTIVE DISEASES AND SCIENCES (2003)
Matrix metalloproteinases and tissue inhibitors of metalloproteinases - Structure, function, and biochemistry
R Visse et al.
CIRCULATION RESEARCH (2003)
Effect of HMG-CoA reductase inhibitors on proliferation and protein synthesis by rat hepatic stellate cells
K Rombouts et al.
JOURNAL OF HEPATOLOGY (2003)
Induction of apoptosis by tanshinone I via cytochrome c release in activated hepatic stellate cells
JY Kim et al.
PHARMACOLOGY & TOXICOLOGY (2003)
Safety and anti-inflammatory activity of curcumin:: A component of tumeric (Curcuma longa)
N Chainani-Wu
JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2003)
Vitamin C as an antioxidant: Evaluation of its role in disease prevention
SJ Padayatty et al.
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2003)
Peroxisome proliferator-activated receptor γ (PPARγ) as a molecular target for the soy phytoestrogen genistein
ZC Dang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hepatocytes express nerve growth factor during liver injury - Evidence for paracrine regulation of hepatic stellate cell apoptosis
F Oakley et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
A blocking peptide for transforming growth factor-beta 1 activation prevents hepatic fibrosis in vivo
H Kondou et al.
JOURNAL OF HEPATOLOGY (2003)
Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice
CD Yu et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Pirfenidone effectively reverses experimental liver fibrosis
L García et al.
JOURNAL OF HEPATOLOGY (2002)
Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production
A Di Sario et al.
JOURNAL OF HEPATOLOGY (2002)
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β
JG Abreu et al.
NATURE CELL BIOLOGY (2002)
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis
C Corpechot et al.
HEPATOLOGY (2002)
Roles of TGF-beta in hepatic fibrosis
AM Gressner et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2002)
Dilinoleoylphosphatidylcholine prevents transforming growth factor-β1-mediated collagen accumulation in cultured rat hepatic stellate cells
Q Cao et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2002)
Evaluation of hepatoprotective potential of jigrine post-treatment against thioacetamide induced hepatic damage
A Ahmad et al.
JOURNAL OF ETHNOPHARMACOLOGY (2002)
Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors
MDA Gaca et al.
JOURNAL OF HEPATOLOGY (2002)
Angiotensin-II type I receptor interaction is a major regulator for liver fibrosis development in rats
H Yoshiji et al.
HEPATOLOGY (2001)
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
MC Wright et al.
GASTROENTEROLOGY (2001)
Pirfenidone inhibits dimethylnitrosamine-induced hepatic fibrosis in rats
S Tada et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2001)
Changes in the dissolution of tolbutamide by a traditional Chinese medicine, Sho-saiko-to (Xiao Chaihu Tang)
N Nishimura et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2001)
Antifibrotic effects of N-acetyl-seryl-aspartyl-lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats
HM Peng et al.
HYPERTENSION (2001)
Treatment of chronic liver diseases with traditional Chinese medicine
BE Wang
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2000)
Deactivation of cultured human liver myofibroblasts by trans-resveratrol, a grapevine-derived polyphenol
S Godichaud et al.
HEPATOLOGY (2000)