4.3 Article

Generative aptamer discovery using RaptGen

Related references

Note: Only part of the references are listed.
Review Nanoscience & Nanotechnology

Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications

Shuaijian Ni et al.

Summary: Aptamers, with oligonucleotide sequences, have capabilities to bind to specific target molecules and are attracting great attention in diverse clinical translations. They offer advantages such as prolonged storage life and feasibility of chemical modifications for enhancing stability.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Biochemical Research Methods

APTANI2: update of aptamer selection through sequence-structure analysis

Jimmy Caroli et al.

BIOINFORMATICS (2020)

Article Multidisciplinary Sciences

In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers

David R. Bell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

RaptRanker: in silico RNA aptamer selection from HT-SELEX experiment based on local sequence and structure information

Ryoga Ishida et al.

NUCLEIC ACIDS RESEARCH (2020)

Review Biochemistry & Molecular Biology

Aptamers: A Review of Their Chemical Properties and Modifications for Therapeutic Application

Tatsuo Adachi et al.

MOLECULES (2019)

Article Biotechnology & Applied Microbiology

A generative model for constructing nucleic acid sequences binding to a protein

Jinho Im et al.

BMC GENOMICS (2019)

Article Chemistry, Multidisciplinary

Automatic Chemical Design Using a Data-Driven Continuous Representation of Molecules

Rafael Gomez-Bombarelli et al.

ACS CENTRAL SCIENCE (2018)

Article Biochemistry & Molecular Biology

Rtools: a web server for various secondary structural analyses on single RNA sequences

Michiaki Hamada et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

Phuong Dao et al.

CELL SYSTEMS (2016)

Article Chemistry, Physical

Searching the Sequence Space for Potent Aptamers Using SELEX in Silico

Qingtong Zhou et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)

Article Biotechnology & Applied Microbiology

Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning

Babak Alipanahi et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery

Jan Hoinka et al.

NUCLEIC ACIDS RESEARCH (2015)

Review Chemistry, Analytical

Aptamer-based biosensors for biomedical diagnostics

Wenhu Zhou et al.

ANALYST (2014)

Article Biochemistry & Molecular Biology

Development of RNA Aptamers Targeting Ebola Virus VP35

Jennifer M. Binning et al.

BIOCHEMISTRY (2013)

Article Biochemistry & Molecular Biology

DNA-Binding Specificities of Human Transcription Factors

Arttu Jolma et al.

Article Chemistry, Analytical

Aptamer-Based Viability Impedimetric Sensor for Bacteria

Mahmoud Labib et al.

ANALYTICAL CHEMISTRY (2012)

Article Biochemical Research Methods

Identification of sequence-structure RNA binding motifs for SELEX-derived aptamers

Jan Hoinka et al.

BIOINFORMATICS (2012)

Article Biochemical Research Methods

ViennaRNA Package 2.0

Ronny Lorenz et al.

ALGORITHMS FOR MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Computational generation and screening of RNA motifs in large nucleotide sequence pools

Namhee Kim et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Biochemical Research Methods

Inferring Binding Energies from Selected Binding Sites

Yue Zhao et al.

PLOS COMPUTATIONAL BIOLOGY (2009)

Article Chemistry, Analytical

Aptamer-based biosensors

Shiping Song et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Using RNA secondary structures to guide sequence motif finding towards single-stranded regions

Michael Hiller et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

Aptamer-based biosensors for the detection of HIV-1 Tat protein

S Tombelli et al.

BIOELECTROCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Selection of the simplest RNA that binds isoleucine

C Lozupone et al.