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Saireito (TJ-114), a Japanese Traditional Herbal Medicine, Reduces 5-Fluorouracil-Induced Intestinal Mucositis in Mice by Inhibiting Cytokine-Mediated Apoptosis in Intestinal Crypt Cells
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PLOS ONE (2015)
Comprehensive Assessment of Host Responses to 5-Fluorouracil-Induced Oral Mucositis through Transcriptomic Analysis
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Inflammasome Activation Is Reactive Oxygen Species Dependent and Mediates Irinotecan-Induced Mucositis through IL-1β and IL-18 in Mice
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Targeted inhibition of IL-18 attenuates irinotecaninduced intestinal mucositis in mice
R. C. P. Lima-Junior et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Activation of p38-MAPK by CXCL4/CXCR3 axis contributes to p53-dependent intestinal apoptosis initiated by 5-fluorouracil
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LED and laser photobiomodulation in the prevention and treatment of oral mucositis: experimental study in hamsters
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Chemotherapy mediates intestinal injury via p53/p53 upregulated modulator of apoptosis (PUMA) signaling pathway
Ya Shi Zhan et al.
JOURNAL OF DIGESTIVE DISEASES (2014)
Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis
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MOLECULAR CANCER (2014)
IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice
R. Guabiraba et al.
MUCOSAL IMMUNOLOGY (2014)
Grape Seed Extract Dose-Responsively Decreases Disease Severity in a Rat Model of Mucositis; Concomitantly Enhancing Chemotherapeutic Effectiveness in Colon Cancer Cells
Ker Yeaw Cheah et al.
PLOS ONE (2014)
S-Nitrosoglutathione Accelerates Recovery from 5-Fluorouracil-Induced Oral Mucositis
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PLOS ONE (2014)
The Role of Wnt/β-Catenin Signaling in Enterocyte Turnover during Methotrexate-Induced Intestinal Mucositis in a Rat
Igor Sukhotnik et al.
PLOS ONE (2014)
IL-1Ra selectively protects intestinal crypt epithelial cells, but not tumor cells, from chemotoxicity via p53-mediated upregulation of p21WAF1 and p27KIP1
Xia Wang et al.
PHARMACOLOGICAL RESEARCH (2014)
Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: The role of inflammation
Chun Seng Lee et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Intravenous Administration of High-Dose Paclitaxel Reduces Gut-Associated Lymphoid Tissue Cell Number and Respiratory Immunoglobulin A Concentrations in Mice
Tomoyuki Moriya et al.
SURGICAL INFECTIONS (2014)
Platelet-rich fibrin has a healing effect on chemotherapy-induced mucositis in hamsters
Koichiro Horii et al.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY (2014)
Pretreatment with Saccharomyces boulardii does not prevent the experimental mucositis in Swiss mice
Tatiani Uceli Maioli et al.
JOURNAL OF NEGATIVE RESULTS IN BIOMEDICINE (2014)
Glutamine protects the small intestinal mucosa in anticancer drug-induced rat enteritis model
Hirokazu Takechi et al.
JOURNAL OF MEDICAL INVESTIGATION (2014)
Sodium Alginate Inhibits Methotrexate-Induced Gastrointestinal Mucositis in Rats
Atsuki Yamamoto et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)
Reduced absorption of long-chain fatty acids during methotrexate-induced gastrointestinal mucositis in the rat
Margot Fijlstra et al.
CLINICAL NUTRITION (2013)
Preclinical Efficacy of Melatonin to Reduce Methotrexate-Induced Oxidative Stress and Small Intestinal Damage in Rats
Viswa Kalyan Kolli et al.
DIGESTIVE DISEASES AND SCIENCES (2013)
Emu oil expedites small intestinal repair following 5-fluorouracil-induced mucositis in rats
Suzanne Mashtoub et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2013)
Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis
Hannelouise Kissow et al.
GUT (2013)
Alteration of the Redox State with Reactive Oxygen Species for 5-Fluorouracil-Induced Oral Mucositis in Hamsters
Fumihiko Yoshino et al.
PLOS ONE (2013)
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11)
Shujuan Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Effects of Streptococcus thermophilus TH-4 in a rat model of doxorubicin-induced mucositis
Hanru Wang et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2013)
Protective effect of bilberry extract as a pretreatment on induced oral mucositis in hamsters
Mehdy Davarmanesh et al.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY (2013)
Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis
Orleancio Gomes R. Azevedo et al.
BMC GASTROENTEROLOGY (2012)
Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation
Roberto Cesar P. Lima-Junior et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2012)
Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine
Hannelouise Kissow et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2012)
Oral Supplementation of Butyrate Reduces Mucositis and Intestinal Permeability Associated with 5-Fluorouracil Administration
Talita Mayra Ferreira et al.
LIPIDS (2012)
Protein fraction of Calotropis procera latex protects against 5-fluorouracil-induced oral mucositis associated with downregulation of pivotal pro-inflammatory mediators
Ana Paula F. Freitas et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2012)
Interleukin 1 receptor antagonist reduces lethality and intestinal toxicity of 5-Fluorouracil in a mouse mucositis model
Zhenqian Wu et al.
BIOMEDICINE & PHARMACOTHERAPY (2011)
CXCL9 attenuated chemotherapy-induced intestinal mucositis by inhibiting proliferation and reducing apoptosis
Xiaodong Han et al.
BIOMEDICINE & PHARMACOTHERAPY (2011)
Non-invasive detection of a palifermin-mediated adaptive response following chemotherapy-induced damage to the distal small intestine of rats
Roger Yazbeck et al.
CANCER BIOLOGY & THERAPY (2011)
Oral ingestion of Streptococcus thermophilus does not affect mucositis severity or tumor progression in the tumor-bearing rat
Katie L. Tooley et al.
CANCER BIOLOGY & THERAPY (2011)
Probiotic factors partially improve parameters of 5-fluorouracil-induced intestinal mucositis in rats
Luca D. Prisciandaro et al.
CANCER BIOLOGY & THERAPY (2011)
Interleukin-1 receptor antagonist attenuates cyclophosphamide-induced mucositis in a murine model
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CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice
Pedro M. G. Soares et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis
C. A. C. X. Medeiros et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Interleukin-1 receptor antagonist reduced apoptosis and attenuated intestinal mucositis in a 5-fluorouracil chemotherapy model in mice
Zhen-Qian Wu et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Selection of Housekeeping Genes for Gene Expression Studies in a Rat Model of Irinotecan-Induced Mucositis
Noor Al-Dasooqi et al.
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Irinotecan-induced alterations in intestinal cell kinetics and extracellular matrix component expression in the dark agouti rat
Noor Al-Dasooqi et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2011)
Protective mechanism of glutamine on the expression of proliferating cell nuclear antigen after cisplatin-induced intestinal mucosal injury
Yuko Tazuke et al.
PEDIATRIC SURGERY INTERNATIONAL (2011)
Orally administered emu oil decreases acute inflammation and alters selected small intestinal parameters in a rat model of mucositis
Ruth J. Lindsay et al.
BRITISH JOURNAL OF NUTRITION (2010)
Serum levels of NF-κB and pro-inflammatory cytokines following administration of mucotoxic drugs
Richard M Logan et al.
CANCER BIOLOGY & THERAPY (2010)
Optimization of the non-invasive C-13-sucrose breath test in a rat model of methotrexate-induced mucositis
K. L. Tooley et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)
Beneficial effects of cathepsin inhibition to prevent chemotherapy-induced intestinal mucositis
I. Alamir et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat
Noor Al-Dasooqi et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2010)
Cisplatin Upregulates Glutamine Transport in Human Intestinal Epithelial Cells: The Protective Mechanism of Glutamine on Intestinal Mucosa After Chemotherapy
Satoko Nose et al.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2010)
Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model
Tien-Yu Huang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Effects of Streptococcus thermophilus TH-4 on intestinal mucositis induced by the chemotherapeutic agent 5-Fluorouracil (5-FU)
Eleanor J. Whitford et al.
CANCER BIOLOGY & THERAPY (2009)
Ozone ameliorates methotrexate-induced intestinal injury in rats
Vural Kesik et al.
CANCER BIOLOGY & THERAPY (2009)
Dietary zinc supplementation and methotrexate-induced small intestinal mucositis in metallothionein-knockout and wild-type mice
Cuong D. Tran et al.
CANCER BIOLOGY & THERAPY (2009)
Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered?
Richard M. Logan et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Protective effects of water-soluble low-molecular-weight β-(1,3-1,6)D-glucan purified from Aureobasidium pullulans GM-NH-1A1 against UFT toxicity in mice
Yoshiyuki Kimura et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2009)
Lyprinol™ only partially improves indicators of small intestinal integrity in a rat model of 5-fluorouracil-induced mucositis
Diana M. Torres et al.
CANCER BIOLOGY & THERAPY (2008)
Light-Emitting Diode Therapy in Chemotherapy-Induced Mucositis
Nancy T. Sacono et al.
LASERS IN SURGERY AND MEDICINE (2008)
Transforming growth factor-alpha stimulates enterocyte proliferation and accelerates intestinal recovery following methotrexate-induced intestinal mucositis in a rat and a cell culture model
Igor Sukhotnik et al.
PEDIATRIC SURGERY INTERNATIONAL (2008)
Changes in the mucus barrier of the rat during 5-fluorouracil-induced gastrointestinal mucositis
Yoichi Saegusa et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2008)
In vivo imaging of oral mucositis in an animal model using optical coherence tomography and optical Doppler tomography
Petra Wilder-Smith et al.
CLINICAL CANCER RESEARCH (2007)
Role of nitric oxide on pathogenesis of 5-fluorouracil induced experimental oral mucositis in hamster
R. F. C. Leitao et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2007)
Green tea polyphenol administration partly ameliorates chemotherapy-induced side effects in the small intestine of mice
Barbara Wessner et al.
JOURNAL OF NUTRITION (2007)
Role of p53 in irinotecan-induced intestinal cell death and mucosal damage
Joanne M. Bowen et al.
ANTI-CANCER DRUGS (2007)
Methotrexate-induced mucositis in mucin 2-deficient mice
Barbara A. E. De Koning et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Intestinal toxicity induced by 5-fluorouracil in pigs: A new preclinical model
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CHEMOTHERAPY (2007)
Evaluation of topical external medicine for 5-fluorouracil-induced oral mucositis in hamsters
Hiromi Mitsuhashi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
A non-invasive method for detection of intestinal mucositis induced by different classes of chemotherapy drugs in the rat
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CANCER BIOLOGY & THERAPY (2006)
Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma
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FASEB JOURNAL (2006)
Diamine oxidase, a plasma biomarker in rats to GI tract toxicity of oral fluorouracil anti-cancer drugs
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Use of the C-13-sucrose breath test to assess chemotherapy-induced small intestinal mucositis in the rat
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CANCER BIOLOGY & THERAPY (2006)
Nutritional supplementation with transforming growth factor-beta, glutamine, and short chain fatty acids minimizes methotrexate-induced injury
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JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2006)
Palifermin reduces diarrhea and increases survival following Irinotecan treatment in tumor-bearing DA rats
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Mitogenic influence of human R-spondin1 on the intestinal epithelium
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SCIENCE (2005)
Effects of the tumour necrosis factor-α inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters
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EUROPEAN JOURNAL OF ORAL SCIENCES (2005)
Lactoferrin reduces methotrexate-induced small intestinal damage, possibly through inhibition of GLP-2-mediated epithelial cell proliferation
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DIGESTIVE DISEASES AND SCIENCES (2004)
An engineered biopolymer prevents mucositis induced by 5-fluorouracil in hamsters
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AMERICAN JOURNAL OF PATHOLOGY (2004)
Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner
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JOURNAL OF SURGICAL RESEARCH (2004)
Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis
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DIGESTIVE DISEASES AND SCIENCES (2004)
Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis
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Response to 5-fluorouracil chemotherapy is modified by dietary folic acid deficiency in ApcMin/+ mice
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Exposure of oral mucosa to bioactive milk factors reduces severity of chemotherapy-induced mucositis in the hamster
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Antitumour activity and adverse reactions of combined treatment,with chitosan and doxorubicin in tumour-bearing mice
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Chemotherapy-induced oral mucositis - Prevention and management
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