Liquid Biopsy and Its Emerging Role in Rheumatology

Liquid biopsy is a rapidly evolving diagnostic technique used to analyze tissue-derived information found in the blood or other bodily fluids. It represents a new way to guide therapeutic decisions, mainly in cancer, but its application in other fields of medicine is still growing. Here, we discuss how liquid biopsy has been used in autoimmune rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus, or primary Sjogren's syndrome. Additionally, in aspect of liquid biopsy, we analyze the molecular biomarkers utilized in the field of rheumatology, including circulating cell-free DNA, microRNA, and proteomic content.

Automated summary

Liquid biopsy is a rapidly evolving diagnostic technique that analyzes tissue-derived information in blood or other bodily fluids. It has the potential to guide therapeutic decisions and has been applied in autoimmune rheumatic diseases.