4.6 Article

Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles

Journal

RSC ADVANCES
Volume 12, Issue 54, Pages 35484-35493

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2ra06306a

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This study reports the self-assembly of hetero-nanoparticles composed of a conjugate with folic acid as the targeting agent and another conjugate with paclitaxel as the active agent. The hetero-nanoparticles with varying percentages of folic acid conjugates are characterized, and their biological activity is determined.
Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined.

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