Journal
ACTA CHIMICA SINICA
Volume 80, Issue 11, Pages 1524-1535Publisher
SCIENCE PRESS
DOI: 10.6023/A22070339
Keywords
covalent organic frameworks; electrochemical biosensor; biological sample; detection
Categories
Funding
- National Key Research and Development Program of China [2019YFA0904104]
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This paper provides a brief summary of the synthesis methods and strategies of COFs, the introduction and classification of electrochemical biosensors, and the application of COFs in electrochemical biosensing for the detection of biological samples. Furthermore, the technical bottlenecks of COFs materials in the field of biosensing and their future development directions are also discussed.
Covalent organic frameworks (COFs) are two-dimensional or three-dimensional organic crystalline materials with nanoscale structural order, which have structural advantages such as high periodicity and modifiability. Electrochemical biosensors based on COFs have the characteristics of ultra-sensitivity, strong specificity, and good repeatability, and have broad prospects in the detection of biological samples. The synthesis methods and strategies of COFs, the introduction and classification of electrochemical biosensors, and the application of COFs in electrochemical biosensing to detect biological samples are briefly summarized. Finally, the technical bottlenecks of COFs materials in the field of biosensing and their future development directions are summarized and discussed.
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