4.2 Article

Association between Exposure to Particulate Matter Air Pollution during Early Childhood and Risk of Attention-Deficit/Hyperactivity Disorder in Taiwan

Publisher

MDPI
DOI: 10.3390/ijerph192316138

Keywords

attention-deficit; hyperactivity disorder (ADHD); particulate matter (PM); National Health Insurance Research Database (NHIRD)

Funding

  1. China Medical University Hospital
  2. Tungs' Taichung Metroharbor Hospital [DMR-111-105]
  3. Taiwan Ministry of Health and Welfare Clinical Trial Center [TTMHH-R1120012]
  4. Ministry of Science and Technology in Taiwan [MOHW111-TDU-B-212-134004]
  5. Ministry of Education in Taiwan [MOST-108-2313-B-005-039-MY3]
  6. [MOE-109-S-0023]

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This study found a significant correlation between early-life exposure to particulate matter PM2.5 and PM10 and attention-deficit/hyperactivity disorder (ADHD).
(1) Background: Recently, a growing number of studies have provided evidence to suggest a strong correlation between air pollution exposure and attention-deficit/hyperactivity disorder (ADHD). In this study, we assessed the relationship between early-life exposure to particulate matter (PM)(10), PM2.(5), and ADHD; (2) Methods: The National Health Insurance Research Database (NHIRD) contains the medical records, drug information, inspection data, etc., of the people of Taiwan, and, thus, could serve as an important research resource. Air pollution data were based on daily data from the Environmental Protection Administration Executive Yuan, R.O.C. (Taiwan). These included particulate matter (PM2.5 and PM10). The two databases were merged according to the living area of the insured and the location of the air quality monitoring station; (3) Results: The highest levels of air pollutants, including PM2.5 (adjusted hazard ratio (aHR) = 1.79; 95% confidence interval (CI) = 1.58-2.02) and PM10 (aHR = 1.53; 95% CI = 1.37-1.70), had a significantly higher risk of ADHD; (4) Conclusions: As such, measures for air quality control that meet the WHO air quality guidelines should be strictly and uniformly implemented by Taiwanese government authorities.

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