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Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells
Yefei Rong et al.
TUMOR BIOLOGY (2013)
Immune Regulatory Function of B Cells
Claudia Mauri et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPH
Li Yin et al.
BLOOD (2012)
KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma
Jianhua Ling et al.
CANCER CELL (2012)
Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
Arianna Calcinotto et al.
CANCER RESEARCH (2012)
ATP-Citrate Lyase: A Key Player in Cancer Metabolism
Nousheen Zaidi et al.
CANCER RESEARCH (2012)
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Haoqiang Ying et al.
CELL (2012)
Conceptual Framework for Cutting the Pancreatic Cancer Fuel Supply
Anne Le et al.
CLINICAL CANCER RESEARCH (2012)
Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma
Shi L. Sheng et al.
FEBS JOURNAL (2012)
Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
Anna N. Mendler et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
Christian M. Metallo et al.
NATURE (2012)
Reduced survival of patients with hepatocellular carcinoma expressing hexokinase II
Lei Gong et al.
MEDICAL ONCOLOGY (2012)
Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression
Tom Latham et al.
NUCLEIC ACIDS RESEARCH (2012)
Hepatitis B Virus Status and Risk of Pancreatic Ductal Adenocarcinoma A Case-Control Study From China
Qiwen Ben et al.
PANCREAS (2012)
Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis
Pierre Sonveaux et al.
PLOS ONE (2012)
Inhibition of Non-Homologous End Joining Repair Impairs Pancreatic Cancer Growth and Enhances Radiation Response
Ying-Hua Li et al.
PLOS ONE (2012)
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer
Nina V. Chaika et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Sucrose Efflux Mediated by SWEET Proteins as a Key Step for Phloem Transport
Li-Qing Chen et al.
SCIENCE (2012)
Cancer Cell Metabolism: One Hallmark, Many Faces
Jason R. Cantor et al.
CANCER DISCOVERY (2012)
Coordinated regulation of myeloid cells by tumours
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Lactate: A Metabolic Key Player in Cancer
Franziska Hirschhaeuser et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice
Tiago C. Leite et al.
FEBS LETTERS (2011)
A Novel Tumor-Associated Pancreatic Glycoprotein Is Internalized by Human Dendritic Cells and Induces Their Maturation
Cecile Franceschi et al.
JOURNAL OF IMMUNOLOGY (2011)
Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
Ryan D. Michalek et al.
JOURNAL OF IMMUNOLOGY (2011)
The metabolic advantage of tumor cells
Maurice Israel et al.
MOLECULAR CANCER (2011)
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
Peng Jiang et al.
NATURE CELL BIOLOGY (2011)
Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma
Guellue Goerguen et al.
BLOOD (2010)
Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis Evidence for stromal-epithelial metabolic coupling
Gemma Migneco et al.
CELL CYCLE (2010)
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
Kathryn E. Wellen et al.
GENES & DEVELOPMENT (2010)
18FLUORODEOXYGLUCOSE PET IS PROGNOSTIC OF PROGRESSION-FREE AND OVERALL SURVIVAL IN LOCALLY ADVANCED PANCREAS CANCER TREATED WITH STEREOTACTIC RADIOTHERAPY
Devin Schellenberg et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)
Sugar transporters for intercellular exchange and nutrition of pathogens
Li-Qing Chen et al.
NATURE (2010)
Helicobacter pylori in Autoimmune Pancreatitis and Pancreatic Carcinoma
Ralf Jesnowski et al.
PANCREATOLOGY (2010)
Activation of β-Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine
Santhakumar Manicassamy et al.
SCIENCE (2010)
Glutathione dysregulation and the etiology and progression of human diseases
Nazzareno Ballatori et al.
BIOLOGICAL CHEMISTRY (2009)
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: N1 versus N2 TAN
Zvi G. Fridlender et al.
CANCER CELL (2009)
The reverse Warburg effect Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
Stephanos Pavlides et al.
CELL CYCLE (2009)
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
Markus Feuerer et al.
NATURE MEDICINE (2009)
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
Y. H. Zhao et al.
ONCOGENE (2009)
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
Taro Hitosugi et al.
SCIENCE SIGNALING (2009)
Cancer cell metabolism: Warburg and beyond
Peggy P. Hsu et al.
CELL (2008)
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
Ralph J. DeBerardinis et al.
CELL METABOLISM (2008)
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Pierre Sonveaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway
Hiroaki Shime et al.
JOURNAL OF IMMUNOLOGY (2008)
The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: A review
M. M. C. Wamelink et al.
JOURNAL OF INHERITED METABOLIC DISEASE (2008)
Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression
Farbod Shojaei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Synergistic up-regulation of Hexokinase-2, glucose transporters and angiogenic factors in pancreatic cancer cells by glucose deprivation and hypoxia
Mitsuteru Natsuizaka et al.
EXPERIMENTAL CELL RESEARCH (2007)
Carcinogenesis of Helicobacter pylori
Pelayo Correa et al.
GASTROENTEROLOGY (2007)
Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
Qiang Gao et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
Shannon M. Gallagher et al.
CANCER RESEARCH (2007)
Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
Gaynor J. Bates et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma.
MI Koukourakis et al.
CANCER RESEARCH (2006)
Hypoxic regulation of PFYFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFYFB genes in gastric cancers
Anastasiya Y. Bobarykina et al.
ACTA BIOCHIMICA POLONICA (2006)
Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 in the human breast and colon malignant tumors
OH Minchenko et al.
BIOCHIMIE (2005)
Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4 - The ancillary protein for the insensitive MCT2 is embigin (gp70)
MC Wilson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
被撤回的出版物: Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity (Retracted article. See vol. 173, pg. 1108, 2023)
H Ito et al.
SURGERY (2004)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
Butyrate downregulates α2β1 integrin:: a possible role in the induction of apoptosis in colorectal cancer cell lines
A Buda et al.
GUT (2003)
Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway - Mechanism of low pH-induced VEGF
L Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells
Q Shi et al.
ONCOGENE (2001)
Cooperation and competition in the evolution of ATP-producing pathways
T Pfeiffer et al.
SCIENCE (2001)
Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems
QA Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
P Kirk et al.
EMBO JOURNAL (2000)