The Seroprevalence of Chlamydia Infection in Sheep in Shanxi Province, China

Simple Summary Chlamydiosis is an important zoonotic disease, which can cause significant harm and economic losses to animal husbandry. So far, there are 15 species in the genus Chlamydia, some of which can infect humans and many mammals including sheep, yaks, pigs, equine animals, and some wild animals. In this study, the indirect hemagglutination assay (IHA) and indirect enzyme-linked immunosorbent assay (ELISA) were used to conduct an epidemiological survey of Chlamydia and Chlamydia abortus (C. abortus) infection in sheep in Shanxi Province, China. The results showed that the overall seroprevalence of Chlamydia infection in sheep in Shanxi Province was 35.67%, and the seroprevalence was associated with the geographical location and management mode. This study provides baseline information for the prevention and control of Chlamydia infection in sheep in Shanxi Province, China. Chlamydia, an obligate intracellular bacterium, can cause chlamydiosis in humans and animals worldwide and also leads to serious economic losses to the sheep industry. However, the information on Chlamydia infection in sheep was limited in Shanxi Province, northern China. In the present study, a total of 984 serum samples of sheep were collected from 11 regions in Shanxi Province, northern China in the autumn of 2020. The antibodies against Chlamydia and Chlamydia abortus were examined by the indirect hemagglutination assay (IHA) and indirect enzyme-linked immunosorbent assay (ELISA), respectively. The result showed that 351 (35.67%, 95% CI 32.68-38.66) of 984 serum samples were positive for Chlamydia, and the seroprevalence ranged from 6.67% to 70.79% among the different regions. In addition, antibodies to C. abortus infection were detected in 78 (7.93%, 95% CI 6.24-9.61) of 984 serum samples, and the seroprevalence ranged from 6.24% to 14.81% among the different regions. This is the first report on the seroprevalence of Chlamydia and C. abortus in sheep in Shanxi province, northern China. The findings provide baseline information for preventing and controlling Chlamydia infection in sheep in Shanxi Province, China.

Automated summary

This study conducted an epidemiological survey of Chlamydia and Chlamydia abortus infection in sheep in Shanxi Province, China. The results showed an overall seroprevalence of Chlamydia infection in sheep in Shanxi Province of 35.67%, with seroprevalence associated with geographical location and management mode. This study provides baseline information for the prevention and control of Chlamydia infection in sheep in Shanxi Province, China.