☆ 4.5 Article

Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA

HUMAN GENOMICS (2022)

Related references

Note: Only part of the references are listed.

Review Biochemistry & Molecular Biology

Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

Saife N. Lone et al.

Summary: Liquid biopsies are non-invasive methods that have revolutionized cancer diagnosis and monitoring. By analyzing tumor-derived entities in body fluids, liquid biopsies provide detailed information about tumor characteristics and can be used for detection, prognosis, and treatment monitoring.

MOLECULAR CANCER (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Cancer Therapy Guided by Mutation Tests: Current Status and Perspectives

Svetlana N. Aleksakhina et al.

Summary: The administration of many cancer drugs is tailored to genetic tests, leading to personalized treatment plans which have significantly improved disease outcomes for a large portion of cancer patients. Genetic testing is now widely used in clinical practice and plays a crucial role in guiding treatment decisions.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Biochemical Research Methods

Quantifying sequencing error and effective sequencing depth of liquid biopsy NGS with UMI error correction

Malene Stochkel Frank et al.

Summary: Liquid biopsies are a minimally invasive method to diagnose and monitor tumor mutations when tissue biopsies are difficult, with cell-free tumor DNA percentage ranging widely. For reliable diagnosis of 0.1% tumor mutations, different methods are required.

BIOTECHNIQUES (2021)

Add to Collection

Review Genetics & Heredity

Liquid Biopsies: Applications for Cancer Diagnosis and Monitoring

Ivana Martins et al.

Summary: Liquid biopsies are a revolutionary approach for cancer management as they can provide a more comprehensive characterization of tumor profiles through the detection of circulating tumor-derived components in biofluids. They have the potential to assist in diagnosis, prognosis, treatment selection, as well as monitoring disease evolution and treatment response in real-time. Despite their value in oncology, some limitations still need to be addressed for their routine clinical implementation.

GENES (2021)

Add to Collection

Article Multidisciplinary Sciences

A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection

Matthew H. Larson et al.

Summary: Cell-free RNA is a promising analyte for cancer detection, with the potential to identify tissue- and subtype-specific biomarkers in breast and lung cancer patients. The presence of dark channel biomarker (DCB) genes in cfRNA from individuals with cancer suggests they could enhance cancer detection in patients with low levels of circulating tumor DNA.

NATURE COMMUNICATIONS (2021)

Add to Collection

Article Engineering, Biomedical

The Translational Status of Cancer Liquid Biopsies

Sinisa Bratulic et al.

Summary: Precision oncology aims to tailor clinical decisions to individual patients by accurately characterizing tumors using omics information. Liquid biopsies, as non-invasive alternatives to traditional tissue biopsies, can provide multiple layers of tumor-specific biological information, leading to discovery of new diagnostic markers with the help of statistical and machine learning approaches. This rapidly advancing field of cancer biomarker research faces both successes and challenges.

REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE (2021)

Add to Collection

Review Biochemical Research Methods

PCR inhibition in qPCR, dPCR and MPS-mechanisms and solutions

Maja Sidstedt et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2020)

Add to Collection

Review Pediatrics

The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review

Ruben Van Paemel et al.

EUROPEAN JOURNAL OF PEDIATRICS (2020)

Add to Collection

Article Oncology

Elevated levels of extracellular vesicles are associated with therapy failure and disease progression in breast cancer patients undergoing neoadjuvant chemotherapy

Lisa Koenig et al.

ONCOIMMUNOLOGY (2018)

Add to Collection

Article Oncology

Exosome-Based Detection of EGFR T790M in Plasma from Non-Small Cell Lung Cancer Patients

Elena Castellanos-Rizaldos et al.

CLINICAL CANCER RESEARCH (2018)

Add to Collection

Review Biochemistry & Molecular Biology

Blood-Based Cancer Biomarkers in Liquid Biopsy: A Promising Non-Invasive Alternative to Tissue Biopsy

Jose Marrugo-Ramirez et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Add to Collection

Article Oncology

Improved EGFR mutation detection using combined exosomal RNA and circulating tumor DNA in NSCLC patient plasma

A. K. Krug et al.

ANNALS OF ONCOLOGY (2018)

Add to Collection

Article Oncology

Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell- Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers

Lino Moehrmann et al.

CLINICAL CANCER RESEARCH (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Mechanism and regulation of the nonsense-mediated decay pathway

Nele Hug et al.

NUCLEIC ACIDS RESEARCH (2016)

Add to Collection

Article Cell Biology

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van Deun et al.

JOURNAL OF EXTRACELLULAR VESICLES (2014)

Add to Collection

© Peeref 2019-2024. All rights reserved.