4.7 Article

Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide- induced diabetic rats

Related references

Note: Only part of the references are listed.
Review Endocrinology & Metabolism

Metformin: Is it a drug for all reasons and diseases?

Chris R. Triggle et al.

Summary: Metformin, a commonly used drug for type 2 diabetes, has shown potential therapeutic effects for other diseases such as polycystic ovary syndrome, cancer, and neurodegenerative diseases. However, there is still debate on whether metformin is effective for all diseases and whether its benefits are solely due to its anti-hyperglycemic and insulin-sensitizing effects.

METABOLISM-CLINICAL AND EXPERIMENTAL (2022)

Review Medicine, General & Internal

Type 2 diabetes

Ehtasham Ahmad et al.

Summary: Type 2 diabetes accounts for nearly 90% of global diabetes cases, with an increasing number of affected individuals, particularly among young people. Early detection and proactive management are crucial for preventing complications and reducing mortality. Technology and precision medicine offer potential improvements to treatment outcomes but face significant barriers.

LANCET (2022)

Review Cardiac & Cardiovascular Systems

Therapeutic Potential of Quercetin to Alleviate Endothelial Dysfunction in Age-Related Cardiovascular Diseases

Olina Dagher et al.

Summary: The vascular endothelium plays crucial roles in maintaining cardiovascular homeostasis, regulating vascular tone, and processing biochemical substances. Dysfunction of endothelial cells may lead to chronic age-related cardiovascular diseases such as ischemic heart disease. Studies have shown that flavonoid compound quercetin, found in various food sources, may help mitigate the risk factors of endothelial dysfunction such as atherosclerosis and hypertension.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

Article Biochemistry & Molecular Biology

Anti-Diabetic Effect of Cotreatment with Quercetin and Resveratrol in Streptozotocin-Induced Diabetic Rats

Dong Kwon Yang et al.

BIOMOLECULES & THERAPEUTICS (2018)

Review Cardiac & Cardiovascular Systems

Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms

John R. Petrie et al.

CANADIAN JOURNAL OF CARDIOLOGY (2018)

Review Cardiac & Cardiovascular Systems

Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword

Xiao-Yan Qi et al.

CARDIOVASCULAR DIABETOLOGY (2018)

Review Nutrition & Dietetics

Quercetin, Inflammation and Immunity

Yao Li et al.

NUTRIENTS (2016)

Review Endocrinology & Metabolism

Update on the treatment of type 2 diabetes mellitus

Juan Jose Marin-Penalver et al.

WORLD JOURNAL OF DIABETES (2016)

Review Biotechnology & Applied Microbiology

Nitric Oxide, Oxidative Stress, and p66Shc Interplay in Diabetic Endothelial Dysfunction

Alessandra Magenta et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Review Pharmacology & Pharmacy

The role of perivascular adipose tissue in vascular smooth muscle cell growth

Chao-Yu Miao et al.

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Article Pharmacology & Pharmacy

Metformin restores endothelial function in aorta of diabetic rats

Cristina M. Sena et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Article Neurosciences

SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans

Anthony J. Donato et al.

JOURNAL OF PHYSIOLOGY-LONDON (2011)

Article Biochemistry & Molecular Biology

CONFIRMATORY STUDIES ON THE ANTIOXIDANT AND ANTIDIABETIC EFFECT OF QUERCETIN IN RATS

M. A. Abdelmoaty et al.

INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2010)

Article Hematology

Protective Role of SIRT1 in Diabetic Vascular Dysfunction

Masayuki Orimo et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes

Takayuki Matsumoto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)

Review Endocrinology & Metabolism

Metformin therapy and clinical uses

John H. B. Scarpello et al.

DIABETES & VASCULAR DISEASE RESEARCH (2008)

Article Biochemistry & Molecular Biology

Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas

Ajay Machha et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2007)

Review Cardiac & Cardiovascular Systems

Dietary antioxidants in preventing atherogenesis

A. C. Kaliora et al.

ATHEROSCLEROSIS (2006)

Article Biochemistry & Molecular Biology

Antidiabetic effects of quercetin in streptozocin-induced diabetic rats

M Vessal et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY (2003)

Article Endocrinology & Metabolism

Metformin decreases platetet superoxide anion production in diabetic patients

P Gargiulo et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2002)

Article Peripheral Vascular Disease

Adhesion molecules and their role in vascular disease

CF Krieglstein et al.

AMERICAN JOURNAL OF HYPERTENSION (2001)

Article Cardiac & Cardiovascular Systems

Improved endothelial function with metformin in type 2 diabetes mellitus

KJ Mather et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2001)