Related references
Note: Only part of the references are listed.RNA-PROTACs: Degraders of RNA-Binding Proteins
Alice Ghidini et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
Adam D. Cotton et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Covalently Engineered Nanobody Chimeras for Targeted Membrane Protein Degradation
Heng Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
Satomi Imaide et al.
NATURE CHEMICAL BIOLOGY (2021)
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties
Peter S. Dragovich et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Aptamer-PROTAC Conjugates (APCs) for Tumor-Specific Targeting in Breast Cancer
Shipeng He et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP
Mengzhu Zheng et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
TF-PROTACs Enable Targeted Degradation of Transcription Factors
Jing Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras
Kusal T. G. Samarasinghe et al.
CELL CHEMICAL BIOLOGY (2021)
Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery
George M. Burslem et al.
CELL (2020)
Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
Maria Maneiro et al.
ACS CHEMICAL BIOLOGY (2020)
Emerging New Concepts of Degrader Technologies
Yu Ding et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2020)
Lysosome-targeting chimaeras for degradation of extracellular proteins
Steven M. Banik et al.
NATURE (2020)
Targeted protein degradation: elements of PROTAC design
Stacey-Lynn Paiva et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2019)
Three decades of nucleic acid aptamer technologies: Lessons learned, progress and opportunities on aptamer development
Tao Wang et al.
BIOTECHNOLOGY ADVANCES (2019)
AUTACs: Cargo-Specific Degraders Using Selective Autophagy
Daiki Takahashi et al.
MOLECULAR CELL (2019)
The dTAG system for immediate and target-specific protein degradation
Behnam Nabet et al.
NATURE CHEMICAL BIOLOGY (2018)
Acute and rapid degradation of endogenous proteins by Trim-Away
Dean Clift et al.
NATURE PROTOCOLS (2018)
Strategies and challenges for the next generation of antibody drug conjugates
Alain Beck et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Analysis of aptamer discovery and technology
Matthew R. Dunn et al.
Nature Reviews Chemistry (2017)
Drugging Undruggable Molecular Cancer Targets
John S. Lazo et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)
Small-molecule kinase inhibitors: an analysis of FDA-approved drugs
Peng Wu et al.
DRUG DISCOVERY TODAY (2016)
Nucleic acid aptamers in cancer research, diagnosis and therapy
Haitao Ma et al.
CHEMICAL SOCIETY REVIEWS (2015)
Small-Molecule Control of Intracellular Protein Levels through Modulation of the Ubiquitin Proteasome System
Dennis L. Buckley et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
NF-κB pathways in hematological malignancies
Chiara Gasparini et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Polypharmacology: Challenges and Opportunities in Drug Discovery
Andrew Anighoro et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution
Grigory S. Filonov et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Plug-and-Play Fluorophores Extend the Spectral Properties of Spinach
Wenjiao Song et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Aptamers: Molecules of great potential
Filip Radom et al.
BIOTECHNOLOGY ADVANCES (2013)
The complexity of NF-κB signaling in inflammation and cancer
Bastian Hoesel et al.
MOLECULAR CANCER (2013)
Targeting cancer cells with nucleic acid aptamers
Laura Cerchia et al.
TRENDS IN BIOTECHNOLOGY (2010)
Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
Evan T. Powers et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
OPINION Is NF-κB a good target for cancer therapy? Hopes and pitfalls
Veronique Baud et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Emerging roles of E2Fs in cancer: an exit from cell cycle control
Hui-Zi Chen et al.
NATURE REVIEWS CANCER (2009)
Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics
Ashley R. Schneekloth et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
NF-KappaB expression correlates with apoptosis and angiogenesis in clear cell renal cell carcinoma tissues
Ibrahim Meteoglu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2008)
Selection and characterization of anti-NF-kappa B p65 RNA aptamers
Susan E. Wurster et al.
RNA (2008)
The challenge of drugging undruggable targets in cancer: Lessons learned from targeting BCL-2 family members
Gregory L. Verdine et al.
CLINICAL CANCER RESEARCH (2007)
H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity
Jing Mi et al.
NUCLEIC ACIDS RESEARCH (2006)
The E2F family: specific functions and overlapping interests
C Attwooll et al.
EMBO JOURNAL (2004)
NF-κB regulation in the immune system
QT Li et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Blockade of NF-κB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
SY Huang et al.
ONCOGENE (2001)
Biochemistry - Adaptive recognition by nucleic acid aptamers
T Hermann et al.
SCIENCE (2000)