Related references
Note: Only part of the references are listed.Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis
Zhen Dai et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms
Sofia Frigerio et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Discovery of 3-(4-(2-((1H-Indol-5-yl)amino)-5-fluoropyrimidin-4yl)-1H-pyrazol-1-yl)propanenitrile Derivatives as Selective TYK2 Inhibitors for the Treatment of Inflammatory Bowel Disease
Chufeng Zhang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Binding patterns and structure-activity relationship of CDK8 inhibitors
Duo Ma et al.
BIOORGANIC CHEMISTRY (2020)
Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease
Kristi A. Leonard et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Epidemiology and Pathogenesis of Ulcerative Colitis
Lillian Du et al.
GASTROENTEROLOGY CLINICS OF NORTH AMERICA (2020)
MicroRNA Biomarkers in IBD-Differential Diagnosis and Prediction of Colitis-Associated Cancer
Jaslin P. James et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
CDK8 as a therapeutic target for cancers and recent developments in discovery of CDK8 inhibitors
Meiyang Xi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19
Masahiko Akamatsu et al.
SCIENCE IMMUNOLOGY (2019)
CDK8-Novel Therapeutic Opportunities
Ingeborg Menzl et al.
PHARMACEUTICALS (2019)
ULCERATIVE COLITIS: TOWARDS REMISSION
Michael Eisenstein
NATURE (2018)
A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease
Hai-Jing Zhong et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
Mattia Cocco et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells
Liv Johannessen et al.
NATURE CHEMICAL BIOLOGY (2017)
Hepatic complications induced by immunosuppressants and biologics in inflammatory bowel disease
My-Linh Tran-Minh et al.
WORLD JOURNAL OF HEPATOLOGY (2017)
JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines
Silvio Danese et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2016)
An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease
Adria Carbo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease
S. Barret Kalindjian et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19
Aurelie Mallinger et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS)
Jonathan B. Baell
JOURNAL OF NATURAL PRODUCTS (2016)
Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases
Paul A. Clarke et al.
ELIFE (2016)
Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen
Aurelie Mallinger et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments
Bruno Rafael Ramos de Mattos et al.
MEDIATORS OF INFLAMMATION (2015)
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
Henry E. Pelish et al.
NATURE (2015)
A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease
Trevor Dale et al.
NATURE CHEMICAL BIOLOGY (2015)
Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells
Thomas B. Sundberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Cytokines in inflammatory bowel disease
Markus F. Neurath
NATURE REVIEWS IMMUNOLOGY (2014)
Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells
Licheng He et al.
TOXICOLOGY (2013)
The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder
E. V. Schneider et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
The regulation of IL-10 production by immune cells
Margarida Saraiva et al.
NATURE REVIEWS IMMUNOLOGY (2010)
A phase I trial with Transgenic bacteria expressing interleukin-10 in Crohn's disease
Henri Braat et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)
Interleukin-10 therapy - Review of a new approach
K Asadullah et al.
PHARMACOLOGICAL REVIEWS (2003)
Share Paper
