4.6 Article

Probiotics with anti-type 2 diabetes mellitus properties: targets of polysaccharides from traditional Chinese medicine

Journal

CHINESE JOURNAL OF NATURAL MEDICINES
Volume 20, Issue 9, Pages 641-655

Publisher

CHINESE JOURNAL NATURAL MEDICINES
DOI: 10.1016/S1875-5364(22)60210-3

Keywords

Traditional Chinese medicine polysaccharide; Prebiotics; Intestinal microflora; Type 2 diabetes mellitus

Funding

  1. Heilongjiang Post-doctoral Research Start-up Fund Funding Project [LBH-Q17167]
  2. Outstanding Youth of Project by Natural Science Foundation of Heilongjiang Province of China [YQ2019H028]

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This article systematically summarizes the anti-diabetic effects of traditional Chinese medicine polysaccharides. These polysaccharides regulate the metabolism of sugar and lipids, improve symptoms such as high blood glucose and abnormal metabolism, and are beneficial for human health.
Traditional Chinese medicine polysaccharides is a biologically active ingredient that is not easy to be digested. It is fermented by intestinal microflora to promote qualitative and selective changes in the composition of the intestinal microbiome, which often result in beneficial effects on the health of the host. People call it prebiotics. In this review, we systematically summarized the anti-diabetic effect of traditional Chinese medicine polysaccharides. These polysaccharides regulate the metabolism of sugar and lipids by inter-influence with the intestinal microflora, and maintain human health, while improving type 2 diabetes-like symptoms such as high blood glucose, and abnormal glucose and lipid metabolism.

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