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Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections

Journal

EMERGING INFECTIOUS DISEASES
Volume 28, Issue 12, Pages 2575-2577

Publisher

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2812.221304

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In this study, it was found that after receiving 3 doses of BNT162b2 vaccine, there was improved neutralization against Omicron BA.1/BA.2 breakthrough infections.
Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.

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