Journal
PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL
Volume 26, Issue 5, Pages 440-448Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.pnsc.2016.09.004
Keywords
Iron oxide nanoparticles; Magnetic hyperthermia; Magneto-structural effects; Magnetic dipolar interactions; Magnetic imaging guided - hyperthermia
Funding
- Solid State and Materials Chemistry Program at NSF [DMR-1253358]
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [1253358] Funding Source: National Science Foundation
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Magnetic iron oxide nanoparticles (IONPs) are heavily explored as diagnostic and therapeutic agents due to their low cost, tunable properties, and biocompatibility. In particular, upon excitation with an alternating current (AC) magnetic field, the NPs generate localized heat that can be exploited for therapeutic hyperthermia treatment of diseased cells or pathogenic microbes. In this review, we focus on how structural changes and inter-particle interactions affect the heating efficiency of iron oxide-based magnetic NPs. Moreover, we present an overview of the different approaches to evaluate the heating performance of IONPs and introduce a new theranostic modality based on magnetic imaging guided-hyperthermia.
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