Journal
MICROMACHINES
Volume 7, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/mi7070123
Keywords
C. elegans; microfluidics; live imaging; electrotaxis; neurobiology; high-throughput screening; drug discovery
Categories
Funding
- CHRP
- NSERC
- ERA
- CRC
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The nematode C. elegans (worm) is a small invertebrate animal widely used in studies related to fundamental biological processes, disease modelling, and drug discovery. Due to their small size and transparent body, these worms are highly suitable for experimental manipulations. In recent years several microfluidic devices and platforms have been developed to accelerate worm handling, phenotypic studies and screens. Here we review major tools and briefly discuss their usage in C. elegans research.
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