Screening and Image-Guided Targeted Biopsy of Prostate Cancer Using 3D Acoustic Radiation Force Impulse (ARFI) Imaging

We have developed a 3D acoustic radiation force impulse (ARFI) imaging system that screens for prostate cancer and provides imaging guidance for a targeted biopsy in a single clinic visit. ARFI and B-mode volumes are acquired by using a rotation stage to sweep a side-fire transrectal ultrasound probe in elevation. After identifying regions of suspicion in the image volumes, the transducer is rotated to each target and a transperineal biopsy is performed. This work describes the data acquisition, processing, and biopsy targeting processes of this system, presents preliminary results from a clinical study assessing the use of ARFI imaging to guide a targeted biopsy, and discusses some challenges and future work.

Automated summary

The study introduces a 3D acoustic radiation force impulse imaging system that screens for prostate cancer and provides imaging guidance for a targeted biopsy in a single clinic visit.