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Surfactant irritations and allergies

Journal

EUROPEAN JOURNAL OF DERMATOLOGY
Volume 32, Issue 6, Pages 677-681

Publisher

JOHN LIBBEY EUROTEXT LTD
DOI: 10.1684/ejd.2022.4290

Keywords

allergic contact dermatitis; contact allergen; cosmetics; irritant contact dermatitis; surfactant

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Surfactants are compounds with hydrophobic tails and hydrophilic heads, which act as a bridge between oil and water. They have various uses, such as cleaning, foaming, and other applications in different fields. However, they also have the potential to damage the skin barrier. The use of new compounds has revealed the potential to cause allergic contact dermatitis, and it is important to have knowledge about this potential and associated dermatitis.
Surfactants are long-chain compounds comprising a hydrophobic tail and a hydrophilic head, lending them the ability to act as a bridge between oil and water. Their detergent, foaming and other properties prove useful in a number of settings, including home and workplace sanitation, cosmetics (rinse and no-rinse cleansers) and medicine. When used on skin, surfactants reduce the superficial surface tension of proteins and lipids on the stratum corneum. This helps to eliminate skin debris such as sebum, oils and dirt, but also presents a risk of damage to the skin barrier. The irritation potential of surfactants has long been common knowledge, but with the development and deployment of novel compounds, notably to replace first-generation, mostly sodium-lauryl-sulphate-based products, their potential to cause allergic contact dermatitis has come to light. Knowledge about this allergic potential and the associated dermatitises must also become commonplace so that contact allergies are considered in the presence of surfactant exposure.

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