Journal
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE
Volume 77, Issue 2, Pages 140-149Publisher
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0036-1579751
Keywords
perineural invasion; perineural spread; head and neck; skin cancer; squamous cell carcinoma; skull base surgery
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The surgical management of perineural spread of head and neck cancers has become an integral part in the contemporary treatment of this pathology. We now understand that tumour spreads within the epineurium and in a continuous fashion. We also can rely on the accuracy of magnetic resonance neurography in detecting and defining the extent of disease. With modern skull base techniques and a greater understanding of the anatomy in this region, specific operations can be designed to help eradicate disease. We review the current approaches and techniques used that enable us to better obtain tumour free margins and hence improve survival.
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