Journal
FRONTIERS IN TOXICOLOGY
Volume 4, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/ftox.2022.958414
Keywords
microplastics; lung disease; epithelial barrier dysfunction; inflammatory response; redox imbalance
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Funding
- Shenzhen Science and Technology Program [JCYJ20210324113006015]
- Guangdong Basic and Applied Basic Research Foundation [2021A1515110433]
- China Postdoctoral Science Foundation [2021M701424]
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Air pollution and microplastics have significant impacts on lung disease, but there is limited understanding of the underlying mechanisms.
Air pollution is one of the major risk factors for lung disease. Microplastics are a ubiquitous environmental pollutant, both indoors and in outdoor air. Microplastics have also been found in human lung tissue and sputum. However, there is a paucity of information on the effects and mechanisms of microplastics on lung disease. In this mini-review, we reviewed the possible mechanisms by which air microplastics' exposure affects lung disease and, at the same time, pointed out the limitations of current studies.
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