Journal
EMERGING INFECTIOUS DISEASES
Volume 28, Issue -, Pages S238-S243Publisher
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2813.212477
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- Department of Defense [19FED1916949IPD]
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This study evaluated the vaccine effectiveness among healthcare personnel in two hospitals in Lima, Peru after receiving COVID-19 vaccination. The results showed an effectiveness of 95% among fully vaccinated participants and 100% among partially vaccinated participants. These findings can provide valuable information for vaccination efforts in the region.
In February 2021, Peru launched a COVID-19 vaccination campaign among healthcare personnel using an inactivated whole-virus vaccine. The manufacturer recommended 2 vaccine doses 21 days apart. We evaluated vaccine effectiveness among an existing multiyear influenza vaccine cohort at 2 hospitals in Lima. We analyzed data on 290 participants followed during February-May 2021. Participants completed a baseline questionnaire and provided weekly self-collected nasal swab samples; samples were tested by real-time reverse transcription PCR. Median participant follow-up was 2 (range 1-11) weeks. We performed multivariable logistic regression and adjusted for preselected characteristics. During the study, 25 (9%) participants tested SARS-CoV-2-positive. We estimated adjusted vaccine effectiveness at 95% (95% CI 70%-99%) among fully vaccinated participants and 100% (95% CI 88%-100%) among partially vaccinated participants. These data can inform the use and acceptance of inactivated whole-virus vaccine and support vaccination efforts in the region.
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