4.0 Article

Entropy Generation Analysis in Blood-Gold Casson Nanofluid Through Horizontal Wavy Channel with Velocity and Thermal Slips: Applications in Skin Diseases

Journal

JOURNAL OF COMPUTATIONAL BIOPHYSICS AND CHEMISTRY
Volume 22, Issue 3, Pages 259-272

Publisher

WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S2737416523400021

Keywords

Entropy generation; blood flow; gold nanoparticles; heat-transfer rate; cancer therapy

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This article investigates the application of gold nanoparticles in cancer treatment. The study finds that the small size and high atomic number of gold nanoparticles can generate heat to destroy tumors. Through mathematical modeling and graphical analysis, the study determines the impact of associated parameters on treatment outcomes, and finds that gold nanoparticles can effectively enhance temperature distribution and destroy cancer cells.
Cancer is known as a deadly disease in which some of the body cells enhance irrepressibly and spread to the other parts of the body. It can start almost anywhere in the human body and these are made up of trillions of cells. Recent researches show that the gold mettle's tiny size particles can be helpful to cure or overcome this disease due to its high atomic number, which can produce the heat that leads to deal with the distortion of tumors. The motivation of this study is to report the entropy generation and heat-transfer analysis in blood flow holding the gold nanoparticles in an asymmetric channel with electro-osmotic phenomena. The mathematical model is developed and simplified by using suitable assumptions. The thermal radiation effects are also incorporated, which are commonly used related to destroying skin diseases. The exact solutions of velocity, shear stress, temperature, stream function, pressure gradient, pressure rise, entropy generation and Bejan number have been obtained. The impact of involved parameters on important physical quantities is highlighted through the graphical method. The results show that the entropy generation and Bejan number enlarge via slip parameter, Casson parameter, Joule heating parameter and heat generation parameter. Results pointed out that the gold nanoparticles enhance the temperature distribution, which makes them capable enough to destroy the cancer cells. It is also noted that the spherical shape is effective in all solutions, but in entropy generation, the platelet shape is more effective than others.

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