Journal
MEDICINA-BUENOS AIRES
Volume 83, Issue 1, Pages 133-137Publisher
MEDICINA (BUENOS AIRES)
Keywords
COVID-19; SARS-CoV-2; pituitary apoplexy; pituitary adenoma; diagnosis; treatment
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This paper reports a case of pituitary apoplexy in a patient with COVID-19 and unknown pituitary macroadenoma, and discusses the potential mechanisms underlying the connection between the two conditions.
Coronavirus disease (SARS-CoV-2/COVID-19) is responsible for a wide variety of extrapulmonary manifestations, among which direct or indirect neurological compromise stands out. Pituitary apoplexy is a clinical and neurosurgical entity of variable severity, usually associated with a pituitary adenoma. Literature is scarce regarding the association between these diseases. This paper reports a case of pituitary apoplexy, manifested concomitantly to the diagnosis of COVID 19 in a patient with unknown pituitary macroadenoma, and its therapeutic management, reviewing the mechanisms potentially underlying the link between both entities.
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