4.4 Article

Risk of endometrial cancer after RRSO in BRCA 1/2 carriers: a multicentre cohort study

Related references

Note: Only part of the references are listed.
Review Medicine, General & Internal

Endometrial Cancer and BRCA Mutations: A Systematic Review

Maria Luisa Gasparri et al.

Summary: This systematic review examines the prevalence of BRCA mutations in endometrial cancer patients and the incidence of endometrial cancer in BRCA mutation women patients. The review finds that BRCA1/2 mutations are present in 4.3% of endometrial cancer patients, with BRCA1 mutations being the most common. However, only 5 studies found a correlation between BRCA mutations and an increased risk of endometrial cancer. The review suggests that routine hysterectomy at the time of risk-reducing salpingo-oophorectomy may not be necessary.

JOURNAL OF CLINICAL MEDICINE (2022)

Article Oncology

Endometrial Cancer Risk in Women With Germline BRCA1 or BRCA2 Mutations: Multicenter Cohort Study

Marthe M. de Jonge et al.

Summary: This Dutch study showed that BRCA1/2 mutation carriers have a two- to threefold increased risk for endometrial cancer compared to the general population, with the highest risk observed in rare subgroups such as serous-like and p53-abnormal EC among BRCA1 mutation carriers.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

Article Oncology

BRCA1 and BRCA2 pathogenic variant carriers and endometrial cancer risk: A cohort study

Sarah J. Kitson et al.

EUROPEAN JOURNAL OF CANCER (2020)

Article Oncology

Germline BRCA-Associated Endometrial Carcinoma Is a Distinct Clinicopathologic Entity

Marthe M. de Jonge et al.

CLINICAL CANCER RESEARCH (2019)

Article Obstetrics & Gynecology

Hysterectomy at the time of risk-reducing surgery in BRCA carriers

Navya Nair et al.

GYNECOLOGIC ONCOLOGY REPORTS (2018)

Article Oncology

Risk of uterine cancer for BRCA1 and BRCA2 mutation carriers

Y. C. Lee et al.

EUROPEAN JOURNAL OF CANCER (2017)

Article Oncology

Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation

Amy P. M. Finch et al.

JOURNAL OF CLINICAL ONCOLOGY (2014)

Article Oncology

Risk of endometrial carcinoma associated with BRCA mutation

DA Levine et al.

GYNECOLOGIC ONCOLOGY (2001)