Dual gold-catalyzed regioselective synthesis of benzofulvenes via 5-endo dig cyclization

An efficient dual gold-catalyzed regioselective synthesis of benzofulvenes has been developed from substituted allyloxy 1,5-diynes via 5-endo dig cyclization. In this intramolecular organic transformation a new C-C bond formation occurs and moderate to very good yields are obtained in one pot.

Automated summary

An efficient method has been developed for the regioselective synthesis of benzofulvenes using dual gold catalysis from substituted allyloxy 1,5-diynes via 5-endo dig cyclization. A new C-C bond formation occurs in this intramolecular organic transformation, resulting in moderate to very good yields in one pot.