4.7 Article

A precise method to monitor hydroxyl radical in natural waters based on a fluoride-containing fluorescence probe

Related references

Note: Only part of the references are listed.
Article Environmental Sciences

Monitoring thiophenols in both environmental water samples and bio-samples: A method based on a fluorescent probe with broad pH adaptation

Junyan Ma et al.

Summary: A novel probe based on intramolecular charge transfer mechanism was presented for the rapid, selective and sensitive detection of highly toxic thiophenols in both environmental and biological systems. The probe exhibited rapid response, broad pH adaptation, high selectivity, large Stokes shift and fluorescence enhancement. It showed low toxicity towards human cells and could be used for detecting thiophenols in living cells, zebrafish and environmental water samples with good recovery.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022)

Article Biochemistry & Molecular Biology

Photoinactivation of Salmonella enterica exposed to 5-aminolevulinic acid: Impact of sensitization conditions and irradiation time

Evelina Polmickaite-Smirnova et al.

Summary: Photodynamic inactivation (PDI) offers a potential alternative to traditional antibiotic therapy for various bacterial infections, including those caused by Gram-negative strains. Exposing bacterial cells to 5-aminolevulinic acid (5-ALA) can make them photosensitive and reduce survival rates after irradiation, but the increase in endogenously produced porphyrins does not necessarily correlate with a proportional reduction in bacterial cells. Additionally, the presence of endogenously produced porphyrins can lead to secondary sensitization of bacterial cells, resulting in a stronger photoinactivation effect compared to externally applied standards.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2022)

Article Medicine, Research & Experimental

Fluorescence probe for selectively monitoring biothiols within cells and mouse depression diagnosis

Junyan Ma et al.

Summary: Depression, a global mental disorder, is linked to oxidative stress in the brain. Cysteine, as a reductive biothiol, plays a role in regulating oxidative conditions in various biological events, including tissue stress. Despite the ongoing challenge of exploring the pathology and physiology of depression, the development of a new method for tracking cysteine levels without interference from other substances is of great significance. In this study, a fluorescence probe has been developed that can selectively detect cysteine over other biothiols. The probe has shown promising performance in cellular applications and mouse brain, providing a new method for cysteine imaging and understanding the pathogenesis of depression. The researchers hope that this work can be applied as a potential chemical approach for diagnosing cysteine-associated diseases in clinical settings.

BIOMEDICINE & PHARMACOTHERAPY (2022)

Article Spectroscopy

A modular template for the design of thiol-triggered sensors and prodrugs

Jessica Renee Knight et al.

Summary: A unique reaction between thiols and alkyl sulfonylbenzothiazole was discovered, leading to the development of thiol-triggered fluorescent sensors and prodrugs with tunable release profiles of payloads.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

Article Biochemistry & Molecular Biology

Piperazine-Coumarin based fluorescence probe with enhanced brightness and solubility for bio-thiol detection and esophageal carcinoma diagnosis

Junyan Ma et al.

Summary: Novel fluorescent probe based on piperazine-coumarin scaffold with enhanced brightness and solubility was successfully developed for efficient detection of bio-thiols. There is great potential for clinical applications in distinguishing pathological tissue from normal tissue.

BIOORGANIC CHEMISTRY (2021)

Article Materials Science, Multidisciplinary

Synthesis of poly (p-phenylene vinylene) derivatives as biopolymer sensor targeting reactive oxygen species (ROS)

Junyan Ma et al.

Summary: Recent studies have shown that cancer cells and their membranes exhibit an exceptionally high concentration of reactive oxygen species (ROS), leading to the development of a method using biopolymers modified from polyphenylvinylene (PPV) as biosensors targeting ROS.

OPTICAL MATERIALS (2021)

Article Biochemistry & Molecular Biology

Ensemble switching unveils a kinetic rheostat mechanism of the eukaryotic thiamine pyrophosphate riboswitch

Junyan Ma et al.

Summary: Recent research on the Arabidopsis thaliana TPP riboswitch reveals a multistep TPP binding process involving multiple riboswitch configurational ensembles and Mg2+ dependence, shedding light on the mechanism of TPP recognition and its impact on expression state.
Article Chemistry, Multidisciplinary

Rapid detection of thioredoxin reductase with a fluorescent probe via a Tag-Sec method

Junyan Ma et al.

Summary: Researchers have developed a Tag-Sec fluorescent probe that can detect both thioredoxin reductase and selenocysteine with high sensitivity and selectivity, along with broad pH tolerance and good water solubility. This concept may serve as a useful guide for designing probes for detecting Sec-containing proteins in clinical diagnosis.

MATERIALS CHEMISTRY FRONTIERS (2021)

Article Chemistry, Multidisciplinary

A coumarin-based biosensor for human hepatocellular carcinoma diagnosis with enhanced brightness and water solubility

Junyan Ma et al.

Summary: This study focused on enhancing the water solubility and brightness of coumarin-based fluorophores by modifying the donor region for detecting biothiols in hepatocellular carcinoma. The newly developed probe showed promise in live cell imaging and demonstrated the ability to differentiate tumor tissues from normal tissues in human hepatocellular carcinoma. It has the potential to serve as a novel tool for clinical diagnosis of hepatocellular carcinoma.

MATERIALS CHEMISTRY FRONTIERS (2021)

Article Chemistry, Multidisciplinary

Sustainable Approach to Azaheterocyclic Acetamides by Decarboxylative Aminoformylation

Zhenxing Zhang et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

Article Environmental Sciences

A rapid and economical method for the quantification of hydrogen peroxide (H2O2) using a modified HPLC apparatus

Omar Tantawi et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Review Chemistry, Multidisciplinary

Coumarin-Based Small-Molecule Fluorescent Chemosensors

Duxia Cao et al.

CHEMICAL REVIEWS (2019)

Article Chemistry, Multidisciplinary

Dual-Site Fluorescent Probe for Visualizing the Metabolism of Cys in Living Cells

Yongkang Yue et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Review Chemistry, Multidisciplinary

Fluorescent chemosensors: the past, present and future

Di Wu et al.

CHEMICAL SOCIETY REVIEWS (2017)

Article Chemistry, Multidisciplinary

A Reversible Fluorescent Probe for Real-Time Quantitative Monitoring of Cellular Glutathione

Zhixue Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Review Chemistry, Multidisciplinary

Environmental Implications of Hydroxyl Radicals (•OH)

Sasho Gligorovski et al.

CHEMICAL REVIEWS (2015)

Article Chemistry, Multidisciplinary

Fluorescence probing of the ferric Fenton reaction via novel chelation

Dhiraj P. Murale et al.

CHEMICAL COMMUNICATIONS (2014)

Review Chemistry, Multidisciplinary

Recent progress in luminescent and colorimetric chemosensors for detection of thiols

Hyo Sung Jung et al.

CHEMICAL SOCIETY REVIEWS (2013)

Article Chemistry, Multidisciplinary

Quinolinium-Based Fluorescent Probes for the Detection of Thiophenols in Environmental Samples and Living Cells

Xiu-Ling Liu et al.

CHEMISTRY-AN ASIAN JOURNAL (2012)

Review Environmental Sciences

Advanced Oxidation Processes for Wastewater Treatment: Formation of Hydroxyl Radical and Application

Jian Long Wang et al.

CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY (2012)

Article Environmental Sciences

Hydroxyl radical generation and oxidative stress in Carassius auratus liver, exposed to pyrene

Yuanyuan Sun et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2008)

Article Chemistry, Analytical

Determination of hydroxyl radical photoproduction rates in natural waters

K Takeda et al.

ANALYTICAL SCIENCES (2004)

Review Biochemistry & Molecular Biology

The Haber-Weiss cycle - 70 years later

WH Koppenol

REDOX REPORT (2001)