Journal
FRONTIERS IN MICROBIOLOGY
Volume 7, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2016.00455
Keywords
dysbiosis; ecosystem; predator; western lifestyle; chronic human conditions; Bdelloviblio bacteriovorus
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Funding
- Investissements d'Avenir programme, Sorbonne Paris Cite [ANR-11-IDEA-0005-02]
- Laboratoire d'excellence INFLAMEX
- Inserm
- Assistance Publique des Hopitaux de Paris
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Most of the Human diseases affecting westernized countries are associated with dysbiosis and loss of microbial diversity in the gut microbiota. The Western way of life, with a wide use of antibiotics and other environmental triggers, may reduce the number of bacterial predators leading to a decrease in microbial diversity of the Human gut. We argue that this phenomenon is similar to the process of ecosystem impoverishment in macro ecology where human activity decreases ecological niches, the size of predator populations, and finally the biodiversity. Such pauperization is fundamental since it reverses the evolution processes, drives life backward into diminished complexity, stability, and adaptability. A simple therapeutic approach could thus be to reintroduce bacterial predators and restore a bacterial diversity of the host microbiota.
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