Recovering sensitivity lost through convection in pure shift NMR

Practical pure shift NMR experiments, especially on instruments equipped with cryoprobes, can sometimes give very disappointing results. Here we show for the first time that this is a consequence of signal loss due to sample convection, and demonstrate a simple adjustment to common pure shift NMR experiments that restores the lost signal. Pure shift NMR experiments using cryoprobes can give very disappointing results. We show that signal losses and phase distortions are a consequence of sample convection, and demonstrate a simple adjustment that restores the lost signal.

Automated summary

This study reveals that practical pure shift NMR experiments using cryoprobes may result in signal loss, and proposes a simple adjustment to recover the lost signal.