Journal
BIOMARKER INSIGHTS
Volume 18, Issue -, Pages -Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/11772719231204508
Keywords
Non-invasive biofluids; multiomics; cancer biomarkers
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Cancer is a complex and heterogeneous disease, and liquid biopsies have emerged as a promising non-invasive method for cancer detection and monitoring. The integration of -omics technologies has further enhanced the capabilities of liquid biopsies, enabling personalized treatment based on individual tumor biology.
Cancer is a complex and heterogeneous disease that poses a significant threat to global health. Early diagnosis and treatment are critical for improving patient outcomes, and the use of liquid biopsies has emerged as a promising approach for cancer detection and monitoring. Traditionally, cancer diagnosis has relied on invasive tissue biopsies, the collection of which can prove challenging for patients and the results of which may not always provide accurate results due to tumor heterogeneity. Liquid biopsies have gained increasing attention as they provide a non-invasive and accessible source of cancer biomarkers, which can be used to diagnose cancer, monitor treatment response, and detect relapse. The integration of -omics technologies, such as proteomics, genomics, and metabolomics, has further enhanced the capabilities of liquid biopsies by introducing precision oncology and enabling the tailoring of treatment for individual patients based on their unique tumor biology. In this review, we will discuss the challenges and advances in the field of cancer liquid biopsies and the integration of -omics technologies for different types of liquid biopsies, including blood, tear, urine, sweat, saliva, and cerebrospinal fluid.
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