Journal
ELIFE
Volume 5, Issue -, Pages -Publisher
ELIFE SCIENCES PUBLICATIONS LTD
DOI: 10.7554/eLife.20062
Keywords
-
Categories
Funding
- Biotechnology and Biological Sciences Research Council [BB/K007564/1]
- Medical Research Council [MR/M000133/1, MRC MC-A652-5PZ80]
- Human Frontier Science Program
- University of Oxford
- Howard Hughes Medical Institute
- Agence Nationale de la Recherche [ANR-12-CHEX-0001-01]
- National Science Foundation [IOS-1257379]
- Imperial College London
- John Fell Fund, University of Oxford
- BBSRC [BB/K007564/1] Funding Source: UKRI
- EPSRC [EP/K000136/1] Funding Source: UKRI
- MRC [MR/M000133/1, MC_UP_1102/13] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/K007564/1] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/K000136/1] Funding Source: researchfish
- Medical Research Council [MR/M000133/1, MC_UP_1102/13] Funding Source: researchfish
Ask authors/readers for more resources
The amphipod crustacean Parhyale hawaiensis is a blossoming model system for studies of developmental mechanisms and more recently regeneration. We have sequenced the genome allowing annotation of all key signaling pathways, transcription factors, and non-coding RNAs that will enhance ongoing functional studies. Parhyale is a member of the Malacostraca clade, which includes crustacean food crop species. We analysed the immunity related genes of Parhyale as an important comparative system for these species, where immunity related aquaculture problems have increased as farming has intensified. We also find that Parhyale and other species within Multicrustacea contain the enzyme sets necessary to perform lignocellulose digestion ('wood eating'), suggesting this ability may predate the diversification of this lineage. Our data provide an essential resource for further development of Parhyale as an experimental model. The first malacostracan genome will underpin ongoing comparative work in food crop species and research investigating lignocellulose as an energy source.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available