Journal
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
Volume 150, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.dci.2023.105067
Keywords
Cordyceps; Hepialus xiaojinensis; Ophiocordyceps sinensis; Infection; Transcriptome; Immune
Categories
Ask authors/readers for more resources
This study focuses on the interaction between Hepialus xiaojinensis larvae and Ophiocordyceps sinensis during the infection process. The results show that the infected third instar larvae enhance antioxidant defense ability, while the infected fourth instar larvae reduce this ability and allocate more energy to growth and development.
Hepialus xiaojinensis is a Lepidopteran insect and one of the hosts for the artificial cultivation of Cordyceps. Ophiocordyceps sinensis can infect and coexist with H. xiaojinensis larvae for a long time. Little studies focused on the interaction process through its early infection stage. In this research, we particularly study the interaction of infected and uninfected larvae in the 3rd (OS-3, CK-3) and 4th (OS-4, CK-4) instars. O. sinensis was distributed within the larvae and accompanied by pathological changes in some tissue structures. In response to O. sinensis infection, OS-3 enhanced the antioxidant defense ability, while OS-4 decreased. The transcriptome analysis showed that OS-3 resisted the invasion of O. sinensis by the immune and nervous systems. Correspondingly, OS-4 reduced immune response and utilized more energy for growth and development. This study provides a comprehensive resource for analyzing the mechanism of H. xiaojinensis and O. sinensis interaction.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available