4.7 Article

An injectable photopolymerizable chitosan hydrogel doped anti-inflammatory peptide for long-lasting periodontal pocket delivery and periodontitis therapy

Related references

Note: Only part of the references are listed.
Article Dentistry, Oral Surgery & Medicine

Silibinin alleviates inflammation-induced bone loss by modulating biological interaction between human gingival fibroblasts and monocytes

Ren-Yeong Huang et al.

Summary: The study found that silibinin can effectively reduce periodontitis-induced bone loss, decrease gingival inflammation and RANKL expression. Silibinin inhibits the differentiation and function of inflammatory cells and osteoclasts, thereby inhibiting inflammation-induced bone loss.

JOURNAL OF PERIODONTOLOGY (2023)

Article Cell Biology

Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells

Jue Shi et al.

Summary: The study demonstrates that Pep-B has anti-inflammatory activity and promotes osteo-/odontoblastic differentiation in LPS-induced inflammatory environment in hDPSCs. These findings suggest the potential role of hDPSCs in repair and regeneration of dental pulp.

MEDIATORS OF INFLAMMATION (2022)

Review Pharmacology & Pharmacy

Strategies and progresses for enhancing targeted antibiotic delivery

Adila Nazli et al.

Summary: Antibiotic resistance is a global health issue and potential risk for society. Traditional antibiotic therapy has limitations, but drug-delivery systems and innovative approaches offer hope for addressing these issues.

ADVANCED DRUG DELIVERY REVIEWS (2022)

Article Dentistry, Oral Surgery & Medicine

Smoking reduces cathelicidin LL-37 and human neutrophil peptide 1-3 levels in the gingival crevicular fluid of patients with periodontitis

Kahena R. Soldati et al.

Summary: Smoking is associated with reduced levels of LL-37 and HNP 1-3 in the gingival crevicular fluid of patients with periodontitis. LL-37 and HNP 1-3 have different expression patterns and correlations with inflammatory mediators in diseased and healthy sites of the periodontium.

JOURNAL OF PERIODONTOLOGY (2021)

Review Chemistry, Multidisciplinary

Local drug delivery systems as therapeutic strategies against periodontitis: A systematic review

Ying Wei et al.

Summary: Periodontitis is a common chronic inflammatory disease affecting nearly 60% of the global population, leading to significant oral health issues. Local drug delivery systems (LDDS) show promise as an adjunctive therapy to traditional treatments, offering higher efficacy and fewer side effects in the management of periodontitis.

JOURNAL OF CONTROLLED RELEASE (2021)

Review Microbiology

Exploring the putative interactions between chronic kidney disease and chronic periodontitis

Niall A. Hickey et al.

CRITICAL REVIEWS IN MICROBIOLOGY (2020)

Article Chemistry, Applied

DLP printing photocurable chitosan to build bio-constructs for tissue engineering

Yi Shen et al.

CARBOHYDRATE POLYMERS (2020)

Review Dentistry, Oral Surgery & Medicine

Sustained-release delivery of antimicrobial drugs for the treatment of periodontal diseases: Fantasy or already reality?

Doron Steinberg et al.

PERIODONTOLOGY 2000 (2020)

Article Biochemistry & Molecular Biology

Glucose-sensitive delivery of metronidazole by using a photo-crosslinked chitosan hydrogel film to inhibit Porphyromonas gingivalis proliferation

Junyu Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Editorial Material Multidisciplinary Sciences

The evolution of antibiotic resistance

R. Craig MacLean et al.

SCIENCE (2019)

Article Dentistry, Oral Surgery & Medicine

Periodontitis and diabetes

Philip M. Preshaw et al.

BRITISH DENTAL JOURNAL (2019)

Article Dentistry, Oral Surgery & Medicine

Periodontal ligament-derived mesenchymal stem cells modulate neutrophil responses via paracrine mechanisms

Monica Yuri Orita Misawa et al.

JOURNAL OF PERIODONTOLOGY (2019)

Review Pharmacology & Pharmacy

Poloxamer Hydrogels for Biomedical Applications

Eleonora Russo et al.

PHARMACEUTICS (2019)

Review Chemistry, Applied

Chitosan-based hydrogels: From preparation to biomedical applications

Michelly C. G. Pella et al.

CARBOHYDRATE POLYMERS (2018)

Article Dentistry, Oral Surgery & Medicine

Gingival crevicular fluid levels of human beta-defensin-1 in type 2 diabetes mellitus and periodontitis

Dogukan Yilmaz et al.

CLINICAL ORAL INVESTIGATIONS (2018)

Article Biotechnology & Applied Microbiology

Activity of human beta defensin-1 and its motif against active and dormant Mycobacterium tuberculosis

Richa Sharma et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)

Review Immunology

Periodontitis: from microbial immune subversion to systemic inflammation

George Hajishengallis

NATURE REVIEWS IMMUNOLOGY (2015)

Review Dentistry, Oral Surgery & Medicine

Global Burden of Severe Periodontitis in 1990-2010: A Systematic Review and Metaregression

N. J. Kassebaum et al.

JOURNAL OF DENTAL RESEARCH (2014)

Article Biochemistry & Molecular Biology

GSK3β is a checkpoint for TNF-α-mediated impaired osteogenic differentiation of mesenchymal stem cells in inflammatory microenvironments

Xiangwei Kong et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)

Article Biochemistry & Molecular Biology

The Novel Human β-Defensin 114 Regulates Lipopolysaccharide (LPS)-mediated Inflammation and Protects Sperm from Motility Loss

Heguo Yu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Engineering, Biomedical

Biodegradable poly(ethylene glycol) hydrogels based on a self-elimination degradation mechanism

Manjeet Deshmukh et al.

BIOMATERIALS (2010)

Review Infectious Diseases

Antibiotic resistance of bacterial biofilms

Niels Hoiby et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2010)

Editorial Material Cardiac & Cardiovascular Systems

Reducing the risk of CVD in patients with periodontitis

Robert J. Genco et al.

NATURE REVIEWS CARDIOLOGY (2010)

Review Microbiology

Periodontitis: a polymicrobial disruption of host homeostasis

Richard P. Darveau

NATURE REVIEWS MICROBIOLOGY (2010)

Article Multidisciplinary Sciences

A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance

TF Mah et al.

NATURE (2003)

Article Dentistry, Oral Surgery & Medicine

Bone turnover markers in serum and periodontal microenvironments

AN Wilson et al.

JOURNAL OF PERIODONTAL RESEARCH (2003)

Review Medicine, General & Internal

Antibiotic resistance of bacteria in biofilms

PS Stewart et al.

LANCET (2001)