Journal
BURNS & TRAUMA
Volume 11, Issue -, Pages -Publisher
OXFORD UNIV PRESS
DOI: 10.1093/burnst/tkad040
Keywords
Wound healing; Biomedical materials; Advanced materials; Tissue regeneration; Inflammation; Regeneration; Anti-bacterial; Cutaneous injury
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This review summarizes the design approaches and applications of smart biomaterials in wound healing. By controlling infection and inflammation, and promoting tissue regeneration, biomaterials play a crucial role in wound healing.
Wound healing is a long-term, multi-stage biological process that mainly includes haemostatic, inflammatory, proliferative and tissue remodelling phases. Controlling infection and inflammation and promoting tissue regeneration can contribute well to wound healing. Smart biomaterials offer significant advantages in wound healing because of their ability to control wound healing in time and space. Understanding how biomaterials are designed for different stages of wound healing will facilitate future personalized material tailoring for different wounds, making them beneficial for wound therapy. This review summarizes the design approaches of biomaterials in the field of anti-inflammatory, antimicrobial and tissue regeneration, highlights the advanced precise control achieved by biomaterials in different stages of wound healing and outlines the clinical and practical applications of biomaterials in wound healing.
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