4.4 Review

Impact of trans-anal versus laparoscopic total mesorectal excision on the surgical and pathologic outcomes of patients with rectal cancer: meta-analysis of randomized controlled trials

Related references

Note: Only part of the references are listed.
Article Surgery

Morbidity, Mortality, and Pathologic Outcomes of Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer Short-term Outcomes From a Multicenter Randomized Controlled Trial

Huashan Liu et al.

Summary: This study aimed to compare the morbidity, mortality, and pathologic outcomes of transanal total mesorectal resection (taTME) and laparoscopic total mesorectal excision (laTME) in patients with rectal cancer. The results showed that there were no significant differences in intraoperative complications, postoperative morbidity, or mortality between the taTME and laTME groups, indicating that experienced surgeons can safely perform taTME in selected patients with rectal cancer.

ANNALS OF SURGERY (2023)

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Transanal versus laparoscopic total mesorectal excision for mid and low rectal cancer (Ta-LaTME study): multicentre, randomized, open-label trial

Xavier Serra-Aracil et al.

Summary: This study suggests that laparoscopic TaTME can avoid conversion to open surgery and has a significantly lower conversion rate compared to laparoscopic total mesorectal excision (LaTME), especially when performed by experienced surgeons. There were no significant differences in postoperative recovery and complications between the two groups, but laparoscopic TaTME had a lower incidence of anastomotic leakage.

BRITISH JOURNAL OF SURGERY (2023)

Review Surgery

Long-term oncologic outcomes of transanal TME compared with transabdominal TME for rectal cancer: a systematic review and meta-analysis

Jae Young Moon et al.

Summary: A meta-analysis of 11 nonrandomized studies found that TaTME may be an alternative to transabdominal TME in terms of long-term oncologic outcomes in patients with rectal cancer, with no significant differences between the two approaches. Well-designed randomized trials are needed for further verification.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2022)

Article Gastroenterology & Hepatology

Pathologic outcomes of transanal versus laparoscopic total mesorectal excision for rectal cancer: a meta-analysis of 26 studies

Laiyuan Li et al.

Summary: This meta-analysis found that TaTME is associated with a lower positive CRM compared to LaTME, with similar pathologic outcomes in terms of DRM, harvested lymph node, and mesorectal excision quality.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2022)

Article Surgery

Comparison of short-term efficacy of transanal total mesorectal excision and laparoscopic total mesorectal excision in low rectal cancer

Jingqing Ren et al.

Summary: There was no significant difference in short-term efficacy between TaTME and LaTME for low rectal cancer, but TaTME had a longer operation time and a greater circumferential resection margin distance.

ASIAN JOURNAL OF SURGERY (2021)

Review Surgery

Prognostic importance of circumferential resection margin in the era of evolving surgical and multidisciplinary treatment of rectal cancer: A systematic review and meta-analysis

Robin Detering et al.

Summary: Circumferential resection margin involvement remains an independent poor prognostic factor for local recurrence and survival in rectal cancer patients, according to the most recent literature. The status of circumferential resection margin can still be used as a short-term surrogate endpoint.

SURGERY (2021)

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Comparison of oncological and functional outcomes and quality of life after transanal or laparoscopic total mesorectal excision for rectal cancer: a systematic review and meta-analysis

I Alimova et al.

Summary: TaTME and LaTME demonstrate similar long-term oncological and functional outcomes as well as quality of life, except for higher LARS scores after TaTME. Current data is mostly based on observational studies, indicating the need for further randomized controlled trials.

TECHNIQUES IN COLOPROCTOLOGY (2021)

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Transanal (TaTME) vs. laparoscopic total mesorectal excision for mid and low rectal cancer: a propensity score-matched analysis of early and long-term outcomes

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Summary: This study compared the outcomes of transanal total mesorectal excision (TaTME) and laparoscopic total mesorectal excision (LapTME) in patients with distal rectal tumors. The results showed that TaTME was associated with a lower conversion to open surgery rate, while having similar post-operative outcomes and similar rates of local recurrence and 3-year survival compared to LapTME.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2021)

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Total mesorectal excision for low and middle rectal cancer: laparoscopic versus transanal approach-a meta-analysis

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Meta-analysis of transanal total mesorectal excision versus laparoscopic total mesorectal excision in management of rectal cancer

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Total Mesorectal Excision Technique-Past, Present, and Future

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CLINICS IN COLON AND RECTAL SURGERY (2020)

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Norwegian moratorium on transanal total mesorectal excision

S. G. Larsen et al.

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Transanal Total Mesorectal Excision: A Novel Approach to Rectal Surgery

Pasithorn A. Suwanabol et al.

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Arnaud Pontallier et al.

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NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance

Patricia Sylla et al.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2010)