4.6 Article

A novel DM9-containing protein 7 involved in regulating the expression of CgMyD88 and CgIL-17 in oyster Crassostrea gigas

Related references

Note: Only part of the references are listed.
Article Immunology

CgDM9CP-5-Integrin-MAPK Pathway Regulates the Production of CgIL-17s and Cgdefensins in the Pacific Oyster, Crassostrea gigas

Yu Liu et al.

Summary: In this study, a novel DM9CP-5 protein was identified from the Pacific oyster and found to be highly expressed in the gill. The protein was able to bind various molecules and interact with CgIntegrin, and its activation was shown to regulate the release of proinflammatory factors and defensins through the MAPK pathway.

JOURNAL OF IMMUNOLOGY (2023)

Article Fisheries

The receptor CgIL-17R1 expressed in granulocytes mediates the CgIL-17 induced haemocytes proliferation in Crassostrea gigas

Wanqing Cao et al.

Summary: In this study, a novel interleukin-17 receptor (CgIL-17R1) was identified from the oyster Crassostrea gigas, and it was found to play a crucial role in mediating the IL-17-induced haemocyte proliferation.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2022)

Article Fisheries

The truncated MyD88s negatively regulates TLR2 signal on expression of IL17-1 in oyster Crassostrea gigas

Siqi Fan et al.

Summary: Toll-like receptor signaling plays a crucial role in the immune response of Pacific oysters. In this study, a receptor called CgTLR2 was identified, which interacts with CgMyD88 proteins and is involved in the regulation of the inflammatory factor CgIL17-1.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2022)

Article Fisheries

A DM9-containing protein from oyster Crassostrea gigas (CgDM9CP-3) mediating immune recognition and encapsulation

Yu Liu et al.

Summary: DM9 domain containing protein (DM9CP) is a pattern recognition molecule found in most organisms except plants. A novel DM9-containing protein (CgDM9CP-3) was identified in Pacific oyster Crassostrea gigas, with high expression in gills and cytomembrane of haemocytes. CgDM9CP-3 can be significantly up-regulated after pathogen stimulations and has the ability to interact with various microorganisms.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2021)

Article Immunology

Identification of a Novel Pattern Recognition Receptor DM9 Domain Containing Protein 4 as a Marker for Pro-Hemocyte of Pacific Oyster Crassostrea gigas

Zhihao Jia et al.

Summary: A novel member of DM9 domain containing protein, CgDM9CP-4, was identified from Pacific oyster, shown to be a mannose-specific binding pattern-recognition receptor enriched in hemocytes and gill. Its transcripts level were decreased after various pathogen stimulations. The recombinant protein displayed broad binding spectrum and was mainly expressed in non-phagocytic cells. This suggests its potential role in immune recognition of pathogens.

FRONTIERS IN IMMUNOLOGY (2021)

Article Parasitology

Agglutination Activity of Fasciola gigantica DM9-1, a Mannose-Binding Lectin

Wansika Phadungsil et al.

Summary: The DM9 domain, a protein unit of 60-75 amino acids, is associated with microbial uptake. FgDM9-1, a lectin with a novel mannose-binding site, can agglutinate bacteria and cause hemagglutination across different ABO blood groups. It is speculated that FgDM9-1, located in parenchymal cells, plays a role in cellular processes involving mannose-carrying molecules.

KOREAN JOURNAL OF PARASITOLOGY (2021)

Article Fisheries

A fibrinogen-related protein mediates the recognition of various bacteria and haemocyte phagocytosis in oyster Crassostrea gigas

Wenwen Yang et al.

Summary: CgFREP1, identified in oysters, serves as a pattern recognition receptor to recognize and agglutinate various bacteria, as well as mediate haemocytes phagocytosis towards Vibrio splendidus.

FISH & SHELLFISH IMMUNOLOGY (2021)

Article Infectious Diseases

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

Eduardo de la Torre-Escudero et al.

PLOS NEGLECTED TROPICAL DISEASES (2019)

Article Fisheries

The oyster immunity

Lingling Wang et al.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2018)

Article Biochemistry & Molecular Biology

Characterization of a Fasciola gigantica protein carrying two DM9 domains reveals cellular relocalization property

Wansika Phadungsil et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2016)

Article Biochemistry & Molecular Biology

Similarity of a 16.5 kDa tegumental protein of the human liver fluke Opisthorchis viverrini to nematode cytoplasmic motility protein

Nipawan Labbunruang et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2016)

Article Fisheries

The immune system and its modulation mechanism in scallop

Linsheng Song et al.

FISH & SHELLFISH IMMUNOLOGY (2015)

Article Multidisciplinary Sciences

Anopheles Gambiae PRS1 Modulates Plasmodium Development at Both Midgut and Salivary Gland Steps

Thomas Chertemps et al.

PLOS ONE (2010)

Article Fisheries

Morphologic, cytometric and functional characterisation of abalone (Haliotis tuberculata) haemocytes

Marie-Agnes Travers et al.

FISH & SHELLFISH IMMUNOLOGY (2008)

Article Cell Biology

SAGE analysis of mosquito salivary gland transcriptomes during Plasmodium invasion

Isabelle Rosinski-Chupin et al.

CELLULAR MICROBIOLOGY (2007)

Article Multidisciplinary Sciences

Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species

N Vodovar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Nitric oxide release by hemocytes of the mussel Mytilus galloprovincialis Lmk was provoked by interleukin-2 but not by lipopolysaccharide

A Novas et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Multidisciplinary Sciences

A protein interaction map of Drosophila melanogaster

L Giot et al.

SCIENCE (2003)