4.7 Article

Orthogonal polymerization of aziridine with cyclic carbonates for constructing amphiphilic block copolymers

Related references

Note: Only part of the references are listed.
Article Polymer Science

Spontaneous alternating copolymerization of aziridines with tosyl isocyanate toward polyureas

Huishan Huang et al.

Summary: We report a new synthetic approach for cyclic polyureas through alternating copolymerization. Aziridines react with tosyl isocyanate spontaneously to produce polyureas with an alternating structure. The synthesized polyureas are found to be cyclic. Calculations indicate that the copolymerization of tosyl isocyanate with ethyleneimine is more favorable kinetically and thermodynamically compared to 2-benzylaziridine.

EUROPEAN POLYMER JOURNAL (2023)

Review Polymer Science

Multi-Polymerization: From Simple to Complex

Meng-Qi Ge et al.

Summary: Multi-polymerization is an important synthetic method for constructing polymers with specific architectures, constitutions, and properties. It can be categorized into three types based on the logical relationship between different mechanisms: sequential/tandem polymerization, orthogonal/concurrent polymerization, and hybrid polymerization. The mutual influence in multi-polymerization is of great significance in this field.

CHINESE JOURNAL OF POLYMER SCIENCE (2023)

Article Biochemistry & Molecular Biology

Dynamic PEG-PLA/Hydroxyurethane Networks Based on Imine Bonds as Reprocessable Elastomeric Biomaterials

Mathilde Grosjean et al.

Summary: The development of dynamic covalent chemistry enables the design of materials that can be reprocessed through internal exchange reactions under thermal stimulus. This study produced PEG-PLA/hydroxyurethane networks incorporating imine bonds, which showed dynamic behavior at moderate temperatures and good reprocessability. This work opens up the possibility of developing a new generation of dynamic materials that combine degradable PEG-PLA copolymers and hydroxyurethane modifiers for on-demand medical devices.

BIOMACROMOLECULES (2023)

Review Chemistry, Organic

Recent advances in the accessibility, synthetic utility, and biological applications of aziridines

Christian Dank et al.

Summary: This review article discusses the recent progress in the biological and chemical evolution of aziridine derivatives, with a focus on the synthesis of aziridines and their transformation reactions. These compounds have shown great potential from both synthetic and pharmacological perspectives and have attracted significant attention due to their promising biological activities.

ORGANIC & BIOMOLECULAR CHEMISTRY (2023)

Review Polymer Science

Overview: Polycarbonates via Ring-Opening Polymerization, Differences between Six- and Five-Membered Cyclic Carbonates: Inspiration for Green Alternatives

Zaher Abdel Baki et al.

Summary: This review focuses on the synthesis of polycarbonate via ring-opening polymerization of cyclic carbonates. It discusses various initiating systems and their mechanisms, as well as the challenges in preparing the polymers and controlling their properties. It highlights the importance of glycerol carbonate as a CO2 fixation agent and its potential as an alternative to Bisphenol A in polycarbonate synthesis.

POLYMERS (2022)

Review Chemistry, Multidisciplinary

Overcoming the Dilemma of Permeability and Stability of Polymersomes through Traceless Cross-Linking

Xiaorui Wang et al.

Summary: Cells and organelles have inspired the development of artificial self-assembled nanostructures, such as liposomes and polymersomes. Liposomes and polymersomes, like cellular structures, consist of an aqueous interior enclosed by a bilayer membrane. While liposomes and polymersomes have been extensively studied, polymersomes have low membrane permeability compared to liposomes. Efforts have been made to improve the permeability of polymersomes, but they often result in decreased stability. This Account discusses a traceless cross-linking approach that reconciles the stability and permeability of polymersomes.

ACCOUNTS OF CHEMICAL RESEARCH (2022)

Article Chemistry, Multidisciplinary

Linear, Graft, and Beyond: Multiblock Copolymers as Next-Generation Compatibilizers

Jeffrey L. Self et al.

Summary: Addressing the issue of plastic waste requires technological breakthroughs, and mechanical recycling into polymer blends is one potential solution. When an appropriately designed compatibilizer is used, the recycled blend can have competitive properties, but the current cost-effectiveness is a challenge that needs further technical development and optimization.

JACS AU (2022)

Review Chemistry, Multidisciplinary

Aliphatic Polycarbonates from Cyclic Carbonate Monomers and Their Application as Biomaterials

Wei Yu et al.

Summary: Aliphatic polycarbonates are gaining attention as biomaterials due to their biocompatibility and tunable degradation, with the ability to introduce functional handles through careful design of cyclic carbonate monomers. These materials have been widely explored for a variety of biomedical applications, from drug delivery to tissue regeneration and vascular graft design, showing great potential for therapeutic use in vitro and in vivo.

CHEMICAL REVIEWS (2021)

Article Chemistry, Multidisciplinary

Mechanical Force for the Transformation of Aziridine into Imine

Sangmin Jung et al.

Summary: This study reports the incorporation of cis-N-phthalimidoaziridine into a macromolecular backbone, leading to the migration of the N-phthalimido group to form an imine under mechanochemical conditions. The imine is then hydrolyzed by water to produce amine and aldehyde. Structural transformations are confirmed through H-1 NMR and FT-IR spectroscopic analyses, and computational simulations are used to propose the reaction mechanism and define the substrate scope.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Biotechnology & Applied Microbiology

Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual

Diana L. Cousminer et al.

Summary: This study used longitudinal bone accrual modeling and genome-wide association studies to identify 40 new genetic loci potentially associated with pediatric bone gain, with 35 loci not previously reported. Functional follow-up and genome editing revealed novel candidate genes impacting bone accrual. The findings suggest that the cell fate decision between osteogenic and adipogenic lineages may be important in normal bone accrual.

GENOME BIOLOGY (2021)

Article Chemistry, Multidisciplinary

Mechanical Force Induces Ylide-Free Cycloaddition of Nonscissible Aziridines

Sangmin Jung et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Review Chemistry, Multidisciplinary

Self-assembly of block copolymers towards mesoporous materials for energy storage and conversion systems

Chen Li et al.

CHEMICAL SOCIETY REVIEWS (2020)

Article Chemistry, Multidisciplinary

Metabolically Active, Fully Hydrolysable Polymersomes

Yunqing Zhu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Chemistry, Multidisciplinary

Block Copolymer Elastomers for Stretchable Electronics

Insang You et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Review Chemistry, Multidisciplinary

Block Copolymer Micelles in Nanomedicine Applications

Horacio Cabral et al.

CHEMICAL REVIEWS (2018)

Article Polymer Science

Diaziridyl Ether of Bisphenol A

Seohyun Kang et al.

MACROMOLECULES (2018)

Review Nanoscience & Nanotechnology

Block copolymers for designing nanostructured porous coatings

Roberto Nistico

BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2018)

Article Chemistry, Multidisciplinary

Fast Access to Amphiphilic Multiblock Architectures by the Anionic Copolymerization of Aziridines and Ethylene Oxide

Tassilo Gleede et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Review Polymer Science

Polymer vesicles: Mechanism, preparation, application, and responsive behavior

Yunqing Zhu et al.

PROGRESS IN POLYMER SCIENCE (2017)

Review Materials Science, Biomaterials

Polyethylenimine: a very useful ionic polymer in the design of immobilized enzyme biocatalysts

Jose J. Virgen-Ortiz et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Review Pharmacology & Pharmacy

Physical and mechanical properties of PLA, and their functions in widespread applications - A comprehensive review

Shady Farah et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Chemistry, Multidisciplinary

Construction of Versatile and Functional Nanostructures Derived from CO2-based Polycarbonates

Yanyan Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micelles

Wei Chen et al.

JOURNAL OF CONTROLLED RELEASE (2010)

Review Chemistry, Multidisciplinary

Coordination-Insertion Copolymerization of Fundamental Polar Monomers

Akifumi Nakamura et al.

CHEMICAL REVIEWS (2009)