Metal-free electrocatalytic nanocomposites of poly azovan blue-decorated graphitic carbon nitride for simultaneously sensing paracetamol and 4-aminophenol

Excessive consumption of paracetamol (PA) and 4-aminophenol (4-AP) can have harmful effects on the human body. This study developed a novel electroanalytical technique that utilizes the nanocomposites of poly azovan blue (PAB)-decorated graphitic carbon nitride (g-C3N4), deposited onto a screen-printed carbon electrode (SPCE), for the concurrent sensing of PA and 4-AP. The fabricated g-C3N4@PAB/SPCE exhibited exceptional synergistic effects, such as a high active electrochemical surface area and excellent electron transfer properties. The electrochemical behavior of g-C3N4@PAB/SPCE for simultaneous PA and 4-AP sensing was evaluated in the linear dynamic ranges of 0.08-75 and 0.05-90 mu M, with the detection limits (S/N = 3) of 0.011 and 0.016 mu M and sensitivities of 2.974 and 2.857 mu A/mu M/cm(-2) for PA and 4-AP, respectively. Additionally, g-C3N4@PAB/SPCE showed long-term stability, high reproducibility (RSD = 2.17%, n = 4), and superior anti-interference capa-bilities. Finally, when g-C3N4@PAB/SPCE was tested for simultaneously sensing both PA and 4-AP in tap water and artificial urine models, it exhibited satisfactory recoveries, demonstrating its potential use for various in-dustrial and clinical applications.

Automated summary

A novel electroanalytical technique utilizing nanocomposites for simultaneous sensing of paracetamol and 4-aminophenol was developed. The technique showed high active electrochemical surface area and excellent electron transfer properties. Satisfactory results were obtained when tested in tap water and artificial urine models, demonstrating its potential for industrial and clinical applications.