☆ 4.7 Article

In silico analysis of prognostic and diagnostic significance of target genes from prostate cancer cell lines derived exomicroRNAs

CANCER CELL INTERNATIONAL (2023)

Related references

Note: Only part of the references are listed.

Review Medicine, General & Internal

Systematic review and meta-analysis of the diagnostic accuracy of prostate-specific antigen (PSA) for the detection of prostate cancer in symptomatic patients

Samuel W. D. Merriel et al.

Summary: The evidence currently available suggests that PSA is highly sensitive but poorly specific for detecting prostate cancer in symptomatic patients. However, limitations in study design and reference test reduce the certainty of this estimate. There is limited evidence regarding the performance of PSA in primary care, where most testing is done.

BMC MEDICINE (2022)

Add to Collection

Review Oncology

Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research

Manuel Ramirez-Garrastacho et al.

Summary: Research on analyzing extracellular vesicles for identifying biomarkers in various diseases, including prostate cancer, has gained attention in the past decade. Despite methodological challenges, new technologies such as nanotechnology offer promise for the future clinical utilization of extracellular vesicles as liquid biomarkers. The knowledge accumulated in the last decade provides a solid foundation for the development of liquid biopsy tests for prostate cancer, which is essential for advancing precision medicine in its treatment.

BRITISH JOURNAL OF CANCER (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Identification of key miRNAs in prostate cancer progression based on miRNA-mRNA network construction

Giulia Dal Santo et al.

Summary: This study analyzed miRNA-mRNA interactions and constructed networks for the onset and progression of prostate cancer, identifying potential biomarkers for differential diagnosis. The selected miRNAs showed better performance in predicting the occurrence and progression of prostate cancer compared to the miRNAs selected by the Boruta algorithm.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2022)

Add to Collection

Review Oncology

Targeting CDK4 and CDK6 in cancer

Shom Goel et al.

Summary: Dysregulation of CDK4 and CDK6 promotes the growth and survival of several cancer types. CDK4/6 inhibitors have become the standard of care for advanced hormone receptor-positive breast cancer. Better understanding of their mechanisms of action and exploring new therapeutic opportunities are crucial.

NATURE REVIEWS CANCER (2022)

Add to Collection

Article Oncology

Cancer Statistics, 2021

Rebecca L. Siegel et al.

Summary: Every year, the American Cancer Society projects the numbers of new cancer cases and deaths in the United States, with the latest data showing a significant decline in lung cancer mortality, while prostate cancer mortality has plateaued and breast and colorectal cancer mortality have slowed. Improvements in treatment have accelerated progress against lung cancer, leading to a record drop in overall cancer mortality.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Add to Collection

Article Oncology

Liquid Biopsy-Based Exo-oncomiRNAs Can Predict Prostate Cancer Aggressiveness

Xavier Ruiz-Plazas et al.

Summary: The study demonstrates that liquid biopsy detection of TWEAK-regulated exo-oncomiRNAs in semen can improve prognosis prediction for prostate cancer (PCa), opening up new avenues for diagnosis and treatment. Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for managing PCa patients. This research identifies potential semen biomarkers and targets regulated by TWEAK that could improve PCa prognosis.

CANCERS (2021)

Add to Collection

Review Oncology

Metastatic Spread in Prostate Cancer Patients Influencing Radiotherapy Response

Daria Klusa et al.

Summary: Radiotherapy and surgery are effective treatments for localized prostate cancer, but once the cancer spreads, the survival rate drops dramatically. Understanding the biological characteristics of PCa metastasis is crucial, and modern imaging technologies can improve early detection of metastases. Unmet clinical needs include biomarkers for targeted radiotherapy and diagnosing minimal residual disease. Monitoring circulating tumor cells during radiotherapy may provide insights into metastatic spread and treatment resistance.

FRONTIERS IN ONCOLOGY (2021)

Add to Collection

Article Oncology

PARP and CDK4/6 Inhibitor Combination Therapy Induces Apoptosis and Suppresses Neuroendocrine Differentiation in Prostate Cancer

Cheng Wu et al.

Summary: The combination therapy of PARP inhibitor and CDK4/6 inhibitor shows synergistic effects in suppressing castration-resistant prostate cancer and neuroendocrine prostate cancer by inhibiting the p-Rb1-E2F1 signaling axis and related target genes, leading to growth inhibition and increased apoptosis.

MOLECULAR CANCER THERAPEUTICS (2021)

Add to Collection

Review Cell Biology

Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination

Madlen Muller et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Add to Collection

Article Cell Biology

4E-T-bound mRNAs are stored in a silenced and deadenylated form

Felix Rasch et al.

GENES & DEVELOPMENT (2020)

Add to Collection

Review Oncology

Cellular and Molecular Progression of Prostate Cancer: Models for Basic and Preclinical Research

Sirin Saranyutanon et al.

CANCERS (2020)

Add to Collection

Article Oncology

microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer

Divya Bhagirath et al.

CANCER RESEARCH (2018)

Add to Collection

Review Urology & Nephrology

Clinical implications of PTEN loss in prostate cancer

Tamara Jamaspishvili et al.

NATURE REVIEWS UROLOGY (2018)

Add to Collection

Article Multidisciplinary Sciences

miRWalk: An online resource for prediction of microRNA binding sites

Carsten Sticht et al.

PLOS ONE (2018)

Add to Collection

Article Cell Biology

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Thery et al.

JOURNAL OF EXTRACELLULAR VESICLES (2018)

Add to Collection

Review Cell Biology

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

Sybren L. N. Maas et al.

TRENDS IN CELL BIOLOGY (2017)

Add to Collection

Article Multidisciplinary Sciences

Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach

Kourosh Zarringhalam et al.

SCIENTIFIC REPORTS (2017)

Add to Collection

Article Pathology

The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma Definition of Grading Patterns and Proposal for a New Grading System

Jonathan I. Epstein et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2016)

Add to Collection

Review Biochemistry & Molecular Biology

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

Mercedes Tkach et al.

CELL (2016)

Add to Collection

Article Genetics & Heredity

Ago1 Interacts with RNA Polymerase II and Binds to the Promoters of Actively Transcribed Genes in Human Cancer Cells

Vera Huang et al.

PLOS GENETICS (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells

Nina Pettersen Hessvik et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2012)

Add to Collection

Article Oncology

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants

Sha Tao et al.

CARCINOGENESIS (2012)

Add to Collection

Article Oncology

Increased cyclin-dependent kinase 6 expression in bladder cancer

Gang Wang et al.

ONCOLOGY LETTERS (2012)

Add to Collection

Article Oncology

Sequence Variants at 22q13 Are Associated with Prostate Cancer Risk

Jielin Sun et al.

CANCER RESEARCH (2009)

Add to Collection

Article Biochemistry & Molecular Biology

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

Lasse Weinmann et al.

CELL (2009)

Add to Collection

Article Gastroenterology & Hepatology

Epigenetic Silencing of MicroRNA miR-107 Regulates Cyclin-Dependent Kinase 6 Expression in Pancreatic Cancer

Kwang-Hyuck Lee et al.

PANCREATOLOGY (2009)

Add to Collection

Article Biochemistry & Molecular Biology

Identification of novel argonaute-associated proteins

G Meister et al.

CURRENT BIOLOGY (2005)

Add to Collection

Article Multidisciplinary Sciences

Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells

JTE Lim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Add to Collection

© Peeref 2019-2024. All rights reserved.