4.4 Article

Synthesis of Indole-2-carboxylates via Condensation of Nitroacetic Esters and 2-Dimethylbenzaldehydes

Journal

CHEMISTRYSELECT
Volume 8, Issue 42, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.202303340

Keywords

2-Dimethylaminobenzaldehyde; Indoles; Nitrite; Nitroacetic esters; Nitrogen heterocycles

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A new operationally simple single step method has been developed for the synthesis of indole-2-carboxylates from 2-dimethylaminobenzaldehydes and nitroacetic acid esters, with yields ranging from 22% to 59%.
A new operationally simple single step method for synthesis indole-2-carboxylates from 2-dimethylaminobenzaldehydes and nitroacetic acid esters in 22-59 % yields has been developed. A new simple single step method for synthesis indole-2-carboxylates from 2-dimethylaminobenzaldehydes and nitroacetic acid esters are presented.image

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