Related references
Note: Only part of the references are listed.Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
Vaibhav Jain et al.
CANCER DISCOVERY (2023)
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Joseph Tintelnot et al.
NATURE (2023)
Autophagy and autophagy-related pathways in cancer
Jayanta Debnath et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2023)
Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer
Subhadip Mukhopadhyay et al.
SCIENCE ADVANCES (2023)
Impact of context-dependent autophagy states on tumor progression
Mohamad Assi et al.
NATURE CANCER (2023)
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression
Phyllis F. Cheung et al.
Nature Communications (2022)
Autophagy in cancer cell remodeling and quality control
Grace A. Hernandez et al.
MOLECULAR CELL (2022)
Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing
Nina Frey et al.
NATURE COMMUNICATIONS (2022)
Targeting autophagy as a therapeutic strategy against pancreatic cancer
Keisuke Yamamoto et al.
JOURNAL OF GASTROENTEROLOGY (2022)
Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer
Mirunalini Ravichandran et al.
CANCER DISCOVERY (2022)
NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins
Naiara Santana-Codina et al.
CANCER DISCOVERY (2022)
Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth
Meng Yuan et al.
NATURE CANCER (2022)
Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
Xiphias Ge Zhu et al.
CELL METABOLISM (2021)
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma
Juan Dubrot et al.
IMMUNITY (2021)
The pleiotropic functions of autophagy in metastasis
Timothy Marsh et al.
JOURNAL OF CELL SCIENCE (2021)
Autophagy in inflammation, infection, and immunometabolism
Vojo Deretic
IMMUNITY (2021)
Transporters at the Interface between Cytosolic and Mitochondrial Amino Acid Metabolism
Keeley G. Hewton et al.
METABOLITES (2021)
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
Hua Su et al.
CANCER CELL (2021)
ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma
Farnaz Sedigheh Takhsha et al.
FRONTIERS IN ONCOLOGY (2021)
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
Rojyar Khezri et al.
EMBO JOURNAL (2021)
Intratumoral T cell clonality and survival in a randomized phase II study of preoperative autophagy inhibition in combination with gemcitabine and nab-paclitaxel treatment in patients with resectable pancreatic cancer.
Pranav Murthy et al.
JOURNAL OF CLINICAL ONCOLOGY (2021)
Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer
Yuanyuan Qiao et al.
NATURE CANCER (2021)
Autophagy Regulates Stress Responses, Metabolism, and Anticancer Immunity
Eileen White et al.
TRENDS IN CANCER (2021)
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer
Jiehui Deng et al.
NATURE CANCER (2021)
Autophagy in tumour immunity and therapy
Houjun Xia et al.
NATURE REVIEWS CANCER (2021)
Ipilimumab and Gemcitabine for Advanced Pancreatic Cancer: A Phase Ib Study
Suneel D. Kamath et al.
ONCOLOGIST (2020)
Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression
Timothy Marsh et al.
DEVELOPMENTAL CELL (2020)
Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer
Keisuke Yamamoto et al.
AUTOPHAGY (2020)
A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
Herbert J. Zeh et al.
CLINICAL CANCER RESEARCH (2020)
Selective Alanine Transporter Utilization Creates a Targetable Metabolic niche in Pancreatic Cancer
Seth J. Parker et al.
CANCER DISCOVERY (2020)
Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy
Muhammad Zaeem Noman et al.
SCIENCE ADVANCES (2020)
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
Keisuke Yamamoto et al.
NATURE (2020)
LC3-Associated Phagocytosis (LAP): A Potentially Influential Mediator of Efferocytosis-Related Tumor Progression and Aggressiveness
Patrick F. Asare et al.
FRONTIERS IN ONCOLOGY (2020)
Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy
Takahiro Yamazaki et al.
NATURE IMMUNOLOGY (2020)
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson et al.
NATURE (2020)
Autophagy in Human Diseases
Noboru Mizushima et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Autophagy Assays for Biological Discovery and Therapeutic Development
Noboru Mizushima et al.
TRENDS IN BIOCHEMICAL SCIENCES (2020)
Autophagy protects tumors from T cell-mediated cytotoxicity via inhibition of TNFα-induced apoptosis
Tara M. Young et al.
SCIENCE IMMUNOLOGY (2020)
Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response
Laura Poillet-Perez et al.
NATURE CANCER (2020)
A framework for advancing our understanding of cancer-associated fibroblasts
Erik Sahai et al.
NATURE REVIEWS CANCER (2020)
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Kirsten L. Bryant et al.
NATURE MEDICINE (2019)
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Conan G. Kinsey et al.
NATURE MEDICINE (2019)
MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival
Chih-Shia Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity
Lindsay DeVorkin et al.
CELL REPORTS (2019)
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
Mark R. Sullivan et al.
ELIFE (2019)
Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer A Phase 2 Randomized Clinical Trial
Thomas B. Karasic et al.
JAMA ONCOLOGY (2019)
Autophagy-Independent Functions of the Autophagy Machinery
Lorenzo Galluzzi et al.
CELL (2019)
Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma: A Phase 2 Randomized Clinical Trial
Eileen M. O'Reilly et al.
JAMA ONCOLOGY (2019)
Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
Christina G. Towers et al.
DEVELOPMENTAL CELL (2019)
Targeting Autophagy in Cancer: Recent Advances and Future Directions
Ravi K. Amaravadi et al.
CANCER DISCOVERY (2019)
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine et al.
CELL (2019)
Autophagy in the renewal, differentiation and homeostasis of immune cells
Alexander J. Clarke et al.
NATURE REVIEWS IMMUNOLOGY (2019)
Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases
Arnaud Pommier et al.
SCIENCE (2018)
Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Catherine S. Grasso et al.
CANCER DISCOVERY (2018)
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and nonautonomous Mechanisms
Annan Yang et al.
CANCER DISCOVERY (2018)
LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
Larissa D. Cunha et al.
CELL (2018)
Autophagy maintains tumour growth through circulating arginine
Laura Poillet-Perez et al.
NATURE (2018)
Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice
Sho Endo et al.
GASTROENTEROLOGY (2017)
Microenvironmental autophagy promotes tumour growth
Nadja S. Katheder et al.
NATURE (2017)
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
Takouhie Mgrditchian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Metabolic Interactions in the Tumor Microenvironment
Costas A. Lyssiotis et al.
TRENDS IN CELL BIOLOGY (2017)
Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
Scott Gettinger et al.
CANCER DISCOVERY (2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
Nicholas McGranahan et al.
CELL (2017)
Recent insights into the function of autophagy in cancer
Ravi Amaravadi et al.
GENES & DEVELOPMENT (2016)
Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment
Hanna Starobinets et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
Cristovao M. Sousa et al.
NATURE (2016)
Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
Jurre J. Kamphorst et al.
CANCER RESEARCH (2015)
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
Michael S. Rooney et al.
CELL (2015)
Whole genomes redefine the mutational landscape of pancreatic cancer
Nicola Waddell et al.
NATURE (2015)
Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma
Xiaoqi Xie et al.
CANCER DISCOVERY (2015)
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Joseph D. Mancias et al.
NATURE (2014)
A dual role for autophagy in a murine model of lung cancer
Shuan Rao et al.
NATURE COMMUNICATIONS (2014)
Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
Annan Yang et al.
CANCER DISCOVERY (2014)
Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
Gizem Karsli-Uzunbas et al.
CANCER DISCOVERY (2014)
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Evaluation of Ipilimumab in Combination With Allogeneic Pancreatic Tumor Cells Transfected With a GM-CSF Gene in Previously Treated Pancreatic Cancer
Dung T. Le et al.
JOURNAL OF IMMUNOTHERAPY (2013)
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
Cosimo Commisso et al.
NATURE (2013)
p53 status determines the role of autophagy in pancreatic tumour development
Mathias T. Rosenfeldt et al.
NATURE (2013)
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
Jaekyoung Son et al.
NATURE (2013)
Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
Daniel D. Von Hoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors
Anne M. Strohecker et al.
CANCER DISCOVERY (2013)
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Haoqiang Ying et al.
CELL (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
Huijun Wei et al.
GENES & DEVELOPMENT (2011)
Pancreatic cancers require autophagy for tumor growth
Shenghong Yang et al.
GENES & DEVELOPMENT (2011)
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2011)
Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma
Richard E. Royal et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Autophagy and the Integrated Stress Response
Guido Kroemer et al.
MOLECULAR CELL (2010)
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
Masaaki Komatsu et al.
CELL (2007)
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
M Komatsu et al.
JOURNAL OF CELL BIOLOGY (2005)
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis
T Munster et al.
ARTHRITIS AND RHEUMATISM (2002)
Share Paper
