☆ 4.7 Review

Self-healing hydrogels based on biological macromolecules in wound healing: A review

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

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The role of natural polymers in bone tissue engineering

Linqi Guo et al.

Summary: Bone is a dynamic self-healing organ with continuous remodeling, but surgical interventions and bone substitutes are needed for repairing large traumatic injuries. Bone tissue engineering aims to repair and regenerate tissues, with natural polymers like collagen and chitosan widely used in the field.

JOURNAL OF CONTROLLED RELEASE (2021)

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Review Materials Science, Multidisciplinary

Preparation of cellulose-based hydrogel: a review

Sarah Husnaini Zainal et al.

Summary: Cellulose, the most abundant natural organic polymer on earth, has low solubility in water and most organic solvents. Specific solvent systems are required for cellulose applications. Hydrogel, as a 3D network structure, can retain a tremendous amount of water and highly depends on the crosslinking property.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2021)

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Review Chemistry, Multidisciplinary

Thiolated polymeric hydrogels for biomedical application: Cross-linking mechanisms

Simona Summonte et al.

Summary: Thiomers, such as thiolated hyaluronic acid and chitosan, are widely studied for their high reactivity in hydrogel synthesis. They exhibit in situ gelling properties and can undergo various click reactions, making them versatile materials for tissue engineering, regenerative medicine, and drug delivery.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Chemistry, Multidisciplinary

In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy

Yue Yin et al.

Summary: The research team developed a transformable hydrogel that can generate nanovaccines for up to 30 days after injection, showing promising potential for effective cancer immunotherapy.

NANO LETTERS (2021)

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Article Multidisciplinary Sciences

Ultrarobust, tough and highly stretchable self-healing materials based on cartilage-inspired noncovalent assembly nanostructure

Yuyan Wang et al.

Summary: The study presents a robust self-healing material with high strength, toughness, and healing efficiency by incorporating high density noncovalent bonds at the interfaces between nanosheets and matrix, overturning the traditional notion that high mechanical strength and healing ability are mutually exclusive in noncovalent bonding materials.

NATURE COMMUNICATIONS (2021)

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Article Engineering, Biomedical

Development of a Biomimetic Hydrogel Based on Predifferentiated Mesenchymal Stem-Cell-Derived ECM for Cartilage Tissue Engineering

Cristina Antich et al.

Summary: The development of a novel biomimetic hydrogel based on decellularized extracellular matrix derived from mesenchymal stem cells for cartilage tissue engineering has shown excellent biocompatibility and the ability to induce chondrogenesis without supplemental factors. This hydrogel also demonstrated the potential to form hyaline cartilage-like tissue after in vivo implantation, highlighting its promise for cartilage repair and regeneration applications.

ADVANCED HEALTHCARE MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Dual-Dynamic-Bond Cross-Linked Antibacterial Adhesive Hydrogel Sealants with On-Demand Removability for Post-Wound-Closure and Infected Wound Healing

Yuqing Liang et al.

Summary: The research developed a smart bioadhesive hydrogel sealant with self-healing and excellent antibacterial activity, showing high effectiveness in wound closure and post-wound-closure care. The hydrogel features autonomous healing, on-demand dissolution, injectability, good biocompatibility, antibacterial properties, multifunctional adhesiveness, and NIR responsiveness. In vivo evaluation demonstrated the great potential of the smart hydrogel in dealing with skin incisions and infected full-thickness skin wounds.

ACS NANO (2021)

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Review Pharmacology & Pharmacy

Supramolecular engineering of hydrogels for drug delivery

Stephane Bernhard et al.

Summary: Supramolecular binding motifs are increasingly utilized in the design of biomaterials, particularly in drug delivery systems. Rational engineering of specific associations enables injectable or sprayable hydrogels, achieving minimally invasive administration in drug delivery.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Review Polymer Science

Recent Advances on Stimuli-Responsive Hydrogels Based on Tissue-Derived ECMs and Their Components: Towards Improving Functionality for Tissue Engineering and Controlled Drug Delivery

Julian A. Serna et al.

Summary: Hydrogels play a vital role in biomedical applications, with dECM-derived hydrogels offering high biomimetic capabilities that can be enhanced through external stimuli for tissue engineering and regenerative medicine advancements.

POLYMERS (2021)

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Review Chemistry, Medicinal

Preparation of Alginate-Based Biomaterials and Their Applications in Biomedicine

Hengtong Zhang et al.

Summary: Alginates are natural polysaccharides extracted from brown marine algae and bacteria, known for their biocompatibility, biodegradability, non-toxicity, and gel formation properties. They can be processed into various forms like hydrogels, microspheres, fibers, and sponges, and have found wide applications in wound healing, tissue repair, and drug delivery in recent years.

MARINE DRUGS (2021)

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Article Multidisciplinary Sciences

Spatiotemporal patterning of photoresponsive DNA-based hydrogels to tune local cell responses

Fujian Huang et al.

Summary: Understanding the effects of surface topographies and modulated stiffness and anisotropic stresses of hydrogels on cell growth is a biophysical challenge. Researchers have introduced photolithographic patterning or two-photon laser scanning confocal microscopy patterning of nucleic acid-based polyacrylamide hydrogel films to control cell behavior. They demonstrate the patterning of physical and biochemical properties to tune local cell responses.

NATURE COMMUNICATIONS (2021)

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Review Chemistry, Multidisciplinary

Functional Hydrogels as Wound Dressing to Enhance Wound Healing

Yongping Liang et al.

Summary: Hydrogels have shown promising advantages as wound dressings due to their excellent biochemical and mechanical properties. This review summarizes the advanced functions of hydrogel dressings, such as antimicrobial, adhesion, hemostasis, anti-inflammatory, substance delivery, self-healing, stimulus response, and conductivity, as well as the emerging wound monitoring feature. The potential applications for different types of wounds, including chronic wounds and focus on infected, burn, and diabetic wounds, are discussed, along with proposed future directions for hydrogel wound dressings in wound healing.

ACS NANO (2021)

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Article Chemistry, Multidisciplinary

Nanoengineered Peptide-Based Antimicrobial Conductive Supramolecular Biomaterial for Cardiac Tissue Engineering

Priyadarshi Chakraborty et al.

Summary: This di-Fmoc-based hydrogelator containing the RGD fragment exhibits good cell adhesion capacity and achieves semiconductivity by incorporating polyaniline into the hydrogel network, demonstrating excellent antibacterial activity and DNA binding capacity while supporting the growth of functional synchronized monolayers of cardiac cells.

ADVANCED MATERIALS (2021)

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Article Biochemistry & Molecular Biology

Curcumin-laden hyaluronic acid-co-Pullulan-based biomaterials as a potential platform to synergistically enhance the diabetic wound repair

Syed Ahmed Shah et al.

Summary: The injectable hydrogel loaded with curcumin demonstrated a significant wound healing potential in a streptozotocin-induced diabetic rat model, showing a faster healing rate compared to other treatment groups. The hydrogel exhibited strong biocompatibility and enhanced cell proliferation, serving as a promising platform for sustained and targeted delivery of hydrophobic moieties.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Biochemistry & Molecular Biology

Shear-thinning and self-healing nanohybrid alginate-graphene oxide hydrogel based on guest-host assembly

S. Soltani et al.

Summary: The study developed a novel nanohybrid shear-thinning hydrogel with fast gelation and variable mechanical and biological properties through self-assembly and crosslinking processes. By controlling macromere concentration and host-guest ratio, the rheological and mechanical properties of hydrogels can be modulated, affecting crosslinking density and network structure. The designed nanohybrid hydrogel exhibited excellent durability and biocompatibility based on the specified parameters.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Materials Science, Biomaterials

Angiogenic Microspheres for the Treatment of a Thin Endometrium

Lanjie Lei et al.

Summary: The study identified poor vascular development as a key cause of thin endometrium and proposed inducing angiogenesis as an effective treatment strategy. By developing angiogenic hydrogel microspheres based on HAMA, the study demonstrated increased drug-loading ability, controlled drug-release rate, promotion of new blood vessel formation, and endometrial regeneration for thin endometrium treatment.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

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Review Biochemistry & Molecular Biology

Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

Huan Cao et al.

Summary: Hydrogel, as a versatile platform, can modulate its physicochemical properties through material engineering to impact cell signaling cascades and fate. Previous studies have revealed the importance of hydrogel properties in influencing cell behaviors and cellular signaling events, providing significant implications for future biomedical applications.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

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Review Materials Science, Biomaterials

Advances in multifunctional chitosan-based self-healing hydrogels for biomedical applications

Yi Ou et al.

Summary: Chitosan, a natural polycationic polysaccharide, plays a vital role in the formation of self-healing hydrogels with multiple functionalities. The self-healing mechanisms involve various physical and chemical interactions, providing strategies for multifunctionalization. Additionally, chitosan-based self-healing hydrogels find wide applications in wound dressings, delivery vehicles, scaffolds, and biological sensors.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Review Polymer Science

A review of the properties and applications of bioadhesive hydrogels

Yingshuo Xiong et al.

Summary: Bioadhesive hydrogels have been extensively studied for their outstanding properties, with potential applications in biomedicine. Researchers summarized the properties, applications, and future prospects of bioadhesive hydrogels.

POLYMER CHEMISTRY (2021)

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Article Materials Science, Biomaterials

Pulmonary tissue-mimetic hydrogel niches for small cell lung cancer cell culture

Mijung Jung et al.

Summary: This study developed a pulmonary tissue-mimetic hydrogel by hybridizing porcine decellularized lung tissue and hyaluronic acid through photopolymerization. The hydrogel exhibited enhanced cell proliferation, drug resistance, and CD44 expression in small cell lung cancer cells.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Chemistry, Multidisciplinary

DNA Hydrogels and Microgels for Biosensing and Biomedical Applications

Fengyun Li et al.

ADVANCED MATERIALS (2020)

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Review Pharmacology & Pharmacy

Silk fibroin for skin injury repair: Where do things stand?

Mazaher Gholipourmalekabadi et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Article Chemistry, Multidisciplinary

A Multifunctional Pro-Healing Zwitterionic Hydrogel for Simultaneous Optical Monitoring of pH and Glucose in Diabetic Wound Treatment

Yingnan Zhu et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

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Article Nanoscience & Nanotechnology

Autonomous Self-Healing Silk Fibroin Injectable Hydrogels Formed via Surfactant-Free Hydrophobic Association

Lei Meng et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Engineering, Biomedical

Self-healing DNA-based injectable hydrogels with reversible covalent linkages for controlled drug delivery

Sayantani Basu et al.

ACTA BIOMATERIALIA (2020)

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Article Chemistry, Applied

Nano-hydroxyapatite enhanced double network hydrogels with excellent mechanical properties for potential application in cartilage repair

Shuchun Gan et al.

CARBOHYDRATE POLYMERS (2020)

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Article Chemistry, Applied

Molecular properties and gut health benefits of enzyme-hydrolyzed konjac glucomannans

Jun-Yi Yin et al.

CARBOHYDRATE POLYMERS (2020)

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Review Dermatology

Optimal Support of Wound Healing: New Insights

Jens Malte Baron et al.

DERMATOLOGY (2020)

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Article Nanoscience & Nanotechnology

Injectable and In Situ-Formable Thiolated Chitosan-Coated Liposomal Hydrogels as Curcumin Carriers for Prevention of In Vivo Breast Cancer Recurrence

Riwang Li et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Agriculture, Multidisciplinary

One-Step Dynamic Imine Chemistry for Preparation of Chitosan-Stabilized Emulsions Using a Natural Aldehyde: Acid Trigger Mechanism and Regulation and Gastric Delivery

Huanle Chen et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)

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Review Chemistry, Multidisciplinary

Tailoring DNA Self-assembly to Build Hydrogels

Jie Chen et al.

TOPICS IN CURRENT CHEMISTRY (2020)

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Review Biotechnology & Applied Microbiology

The Delivery of RNA-Interference Therapies Based on Engineered Hydrogels for Bone Tissue Regeneration

Tingting Yu et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Review Engineering, Biomedical

Decellularization systems and devices: State-of-the-art

Deepak Choudhury et al.

ACTA BIOMATERIALIA (2020)

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Article Chemistry, Applied

Synthesis of quaternised guar gum using Taguchi L(16) orthogonal array

Rakhi Tyagi et al.

CARBOHYDRATE POLYMERS (2020)

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Review Biochemistry & Molecular Biology

Research status of self-healing hydrogel for wound management: A review

Andi Zhang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Materials Science, Biomaterials

Novel Self-Healing Hydrogel with Injectable, pH-Responsive, Strain-Sensitive, Promoting Wound-Healing, and Hemostatic Properties Based on Collagen and Chitosan

Cuicui Ding et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

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Article Biochemistry & Molecular Biology

Photoconfigurable, Cell-Remodelable Disulfide Cross-linked Hyaluronic Acid Hydrogels

Linke Wu et al.

BIOMACROMOLECULES (2020)

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Article Engineering, Multidisciplinary

Preparation of a chitosan/carboxymethyl chitosan/AgNPs polyelectrolyte composite physical hydrogel with self-healing ability, antibacterial properties, and good biosafety simultaneously, and its application as a wound dressing

Jueying Yang et al.

COMPOSITES PART B-ENGINEERING (2020)

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Article Polymer Science

Stress Relaxation and Underlying Structure Evolution in Tough and Self-Healing Hydrogels

Kunpeng Cui et al.

ACS MACRO LETTERS (2020)

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Review Biochemistry & Molecular Biology

Wound healing: cellular mechanisms and pathological outcomes

Holly N. Wilkinson et al.

OPEN BIOLOGY (2020)

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Article Nanoscience & Nanotechnology

Injectable Adhesive Self-Healing Multicross-Linked Double-Network Hydrogel Facilitates Full-Thickness Skin Wound Healing

Bo Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Materials Science, Biomaterials

The fabrication of a highly efficient self-healing hydrogel from natural biopolymers loaded with exosomes for the synergistic promotion of severe wound healing

Chunyao Wang et al.

BIOMATERIALS SCIENCE (2020)

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Article Materials Science, Biomaterials

A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer

Lairong Ding et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Materials Science, Biomaterials

A self-adapting hydrogel based on chitosan/oxidized konjac glucomannan/AgNPs for repairing irregular wounds

Yixin Wang et al.

BIOMATERIALS SCIENCE (2020)

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Article Chemistry, Multidisciplinary

Synthesis of hyaluronic acid hydrogels by crosslinking the mixture of high-molecular-weight hyaluronic acid and low-molecular-weight hyaluronic acid with 1,4-butanediol diglycidyl ether

Yu Xue et al.

RSC ADVANCES (2020)

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Article Polymer Science

Self-Healing Polymeric Hydrogel Formed by Metal-Ligand Coordination Assembly: Design, Fabrication, and Biomedical Applications

Liyang Shi et al.

MACROMOLECULAR RAPID COMMUNICATIONS (2019)

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Article Polymer Science

Flexible aromatic disulfide monomers for high-performance self-healable linear and cross-linked poly(urethane-urea) coatings

Sil Nevejans et al.

POLYMER (2019)

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Review Engineering, Biomedical

Decellularized Extracellular Matrix Materials for Cardiac Repair and Regeneration

Donald Bejleri et al.

ADVANCED HEALTHCARE MATERIALS (2019)

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Review Engineering, Biomedical

Advances in injectable self-healing biomedical hydrogels

Yujie Tu et al.

ACTA BIOMATERIALIA (2019)

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Article Chemistry, Physical

Stretchable, Injectable, and Self-Healing Conductive Hydrogel Enabled by Multiple Hydrogen Bonding toward Wearable Electronics

Jingsi Chen et al.

CHEMISTRY OF MATERIALS (2019)

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Article Pharmacology & Pharmacy

3D printed chitosan dressing crosslinked with genipin for potential healing of chronic wounds

Forough Hafezi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Review Biochemistry & Molecular Biology

Chitosan-Based (Nano)Materials for Novel Biomedical Applications

Gregor Kravanja et al.

MOLECULES (2019)

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Article Chemistry, Multidisciplinary

An Injectable Hyaluronic Acid-Based Composite Hydrogel by DA Click Chemistry With pH Sensitive Nanoparticle for Biomedical Application

Xiaohong Hu et al.

FRONTIERS IN CHEMISTRY (2019)

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Article Chemistry, Applied

Self-healable and dual-functional guar gum-grafted-polyacrylamidoglycolic acid-based hydrogels with nano-silver for wound dressings

Ramasubba Reddy Palem et al.

CARBOHYDRATE POLYMERS (2019)

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Article Chemistry, Applied

An injectable self-healing hydrogel-cellulose nanocrystals conjugate with excellent mechanical strength and good biocompatibility

WenBo Du et al.

CARBOHYDRATE POLYMERS (2019)

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Article Polymer Science

Guar gum: Versatile natural polymer for drug delivery applications

Archana George et al.

EUROPEAN POLYMER JOURNAL (2019)

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Article Polymer Science

Hydrophobic association hydrogels with excellent mechanical and self-healing properties

Haicheng Jiang et al.

EUROPEAN POLYMER JOURNAL (2019)

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Review Biochemistry & Molecular Biology

Bactericidal and Cytotoxic Properties of Silver Nanoparticles

Chengzhu Liao et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Review Physiology

WOUND HEALING: A CELLULAR PERSPECTIVE

Melanie Rodrigues et al.

PHYSIOLOGICAL REVIEWS (2019)

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Article Polymer Science

Self-healing hydrogels with stimuli responsiveness based on acylhydrazone bonds

Chengyuan Sun et al.

POLYMER (2019)

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Article Instruments & Instrumentation

pH-responsive calcium alginate hydrogel laden with protamine nanoparticles and hyaluronan oligosaccharide promotes diabetic wound healing by enhancing angiogenesis and antibacterial activity

Tao Wang et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2019)

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Review Chemistry, Multidisciplinary

The Collagen Suprafamily: From Biosynthesis to Advanced Biomaterial Development

Anna Sorushanova et al.

ADVANCED MATERIALS (2019)

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Article Chemistry, Multidisciplinary

3D-printable self-healing and mechanically reinforced hydrogels with host-guest non-covalent interactions integrated into covalently linked networks

Zhifang Wang et al.

MATERIALS HORIZONS (2019)

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Article Nanoscience & Nanotechnology

Encapsulation of Curcumin Nanoparticles with MMP9-Responsive and Thermos-Sensitive Hydrogel Improves Diabetic Wound Healing

Juan Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Chemistry, Applied

Gum Arabic: A promising candidate for the construction of physical hydrogels exhibiting highly stretchable, self-healing and tensility reinforcing performances

Dongbei Wu et al.

CARBOHYDRATE POLYMERS (2018)

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Article Pharmacology & Pharmacy

Application of hyaluronic acid as carriers in drug delivery

Gangliang Huang et al.

DRUG DELIVERY (2018)

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Review Chemistry, Applied

Modifications of konjac glucomannan for diverse applications

Fan Zhu

FOOD CHEMISTRY (2018)

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Article Biochemistry & Molecular Biology

Glycogen-based self-healing hydrogels with ultra-stretchable, flexible, and enhanced mechanical properties via sacrificial bond interactions

Imtiaz Hussain et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

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Article Materials Science, Biomaterials

Synthesis and characterization of a novel double cross-linked hydrogel based on Diels-Alder click reaction and coordination bonding

Shubin Li et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

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Review Polymer Science

Dynamic covalent polymer hydrogels and organogels crosslinked through acylhydrazone bonds: synthesis, characterization and applications

Demetris E. Apostolides et al.

POLYMER INTERNATIONAL (2018)

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Article Materials Science, Biomaterials

Noninvasive rapid bacteria-killing and acceleration of wound healing through photothermal/photodynamic/copper ion synergistic action of a hybrid hydrogel

Mu Li et al.

BIOMATERIALS SCIENCE (2018)

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Article Physiology

The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes

Paulina Krzyszczyk et al.

FRONTIERS IN PHYSIOLOGY (2018)

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Article Nanoscience & Nanotechnology

Construction of Injectable Self-Healing Macroporous Hydrogels via a Template-Free Method for Tissue Engineering and Drug Delivery

Lei Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Nanoscience & Nanotechnology

Ultratough, Self-Healing, and Tissue-Adhesive Hydrogel for Wound Dressing

Tao Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Engineering, Biomedical

Immunomodulatory injectable silk hydrogels maintaining functional islets and promoting anti-inflammatory M2 macrophage polarization

Manishekhar Kumar et al.

BIOMATERIALS (2018)

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Article Chemistry, Applied

An injectable self-healing hydrogel with adhesive and antibacterial properties effectively promotes wound healing

Honglei Chen et al.

CARBOHYDRATE POLYMERS (2018)

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Article Infectious Diseases

Social network analysis for poultry HPAI transmission

Xiangdong Sun et al.

TRANSBOUNDARY AND EMERGING DISEASES (2018)

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Editorial Material Medicine, General & Internal

Management of Chronic Wounds-2018

Ruth Ellen Jones et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

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Review Agriculture, Multidisciplinary

Manufacture and Properties of Glucomannans and Glucomannooligosaccharides Derived from Konjac and Other Sources

Belen Gomez et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

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Article Materials Science, Biomaterials

Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation

Jisun Park et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

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Review Multidisciplinary Sciences

Advances in engineering hydrogels

Yu Shrike Zhang et al.

SCIENCE (2017)

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Article Polymer Science

One-Pot Preparation of Autonomously Self-Healable Elastonneric Hydrogel from Boric Acid and Random Copolymer Bearing Hydroxyl Groups

Yiming Chen et al.

ACS MACRO LETTERS (2017)

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Article Nanoscience & Nanotechnology

A Facile Approach To Prepare Tough and Responsive Ultrathin Physical Hydrogel Films as Artificial Muscles

Ye Tian et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Review Biotechnology & Applied Microbiology

Biocompatibility of hydrogel-based scaffolds for tissue engineering applications

Sheva Naahidi et al.

BIOTECHNOLOGY ADVANCES (2017)

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Article Engineering, Biomedical

Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing

Xin Zhao et al.

BIOMATERIALS (2017)

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Review Chemistry, Multidisciplinary

Designing Hydrogels for On-Demand Therapy

Nuria Oliva et al.

ACCOUNTS OF CHEMICAL RESEARCH (2017)

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Article Chemistry, Multidisciplinary

New Developments in Smart Bandage Technologies for Wound Diagnostics

Anna McLister et al.

ADVANCED MATERIALS (2016)

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Article Chemistry, Applied

Properties and in vitro drug release of hyaluronic acid-hydroxyethyl cellulose hydrogels for transdermal delivery of isoliquiritigenin

Bong Ju Kong et al.

CARBOHYDRATE POLYMERS (2016)

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Article Chemistry, Multidisciplinary

Multiple-color aggregation-induced emission (AIE) molecules as chemodosimeters for pH sensing

Qi Feng et al.

CHEMICAL COMMUNICATIONS (2016)

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Review Chemistry, Multidisciplinary

Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications

Juan Li et al.

CHEMICAL SOCIETY REVIEWS (2016)

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Article Chemistry, Multidisciplinary

Driving Forces for Oppositely Charged Polyion Association in Aqueous Solutions: Enthalpic, Entropic, but Not Electrostatic

Jingcheng Fu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Article Nanoscience & Nanotechnology

Multifunctional Hydrogel with Good Structure Integrity, Self-Healing, and Tissue-Adhesive Property Formed by Combining Die Is Alder Click Reaction and Acylhydrazone Bond

Feng Yu et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

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Article Chemistry, Multidisciplinary

Acylhydrazones as Reversible Covalent Crosslinkers for Self-Healing Polymers

Natascha Kuhl et al.

ADVANCED FUNCTIONAL MATERIALS (2015)

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Article Biochemistry & Molecular Biology

Injectable and Self-Healing Dynamic Hydrogels Based on Metal(I)-Thiolate/Disulfide Exchange as Biomaterials with Tunable Mechanical Properties

Pablo Casuso et al.

BIOMACROMOLECULES (2015)

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Article Chemistry, Applied

Alkali-treated konjac glucomannan film as a novel wound dressing

Yi-Cheng Huang et al.

CARBOHYDRATE POLYMERS (2015)

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Review Engineering, Biomedical

Design of cell-matrix interactions in hyaluronic acid hydrogel scaffolds

Jonathan Lam et al.

ACTA BIOMATERIALIA (2014)

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Review Chemistry, Multidisciplinary

25th Anniversary Article: Designer Hydrogels for Cell Cultures: A Materials Selection Guide

Julian Thiele et al.

ADVANCED MATERIALS (2014)

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Article Biochemistry & Molecular Biology

A Nanostructured Synthetic Collagen Mimic for Hemostasis

Vivek A. Kumar et al.

BIOMACROMOLECULES (2014)

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Article Immunology

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

Dror S. Shouval et al.

IMMUNITY (2014)

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Review Medicine, Research & Experimental

Curcumin as a wound healing agent

Dania Akbik et al.

LIFE SCIENCES (2014)

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Review Multidisciplinary Sciences

Advances in skin grafting and treatment of cutaneous wounds

Bryan K. Sun et al.

SCIENCE (2014)

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Review Chemistry, Multidisciplinary

Designing degradable hydrogels for orthogonal control of cell microenvironments

Prathamesh M. Kharkar et al.

CHEMICAL SOCIETY REVIEWS (2013)

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Review Biochemistry & Molecular Biology

Galactomannan: A versatile biodegradable seed polysaccharide

Vipul D. Prajapati et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2013)

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Article Multidisciplinary Sciences

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

Mona Saffarzadeh et al.

PLOS ONE (2012)

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Article Chemistry, Multidisciplinary

pH responsive self-healing hydrogels formed by boronate-catechol complexation

Lihong He et al.

CHEMICAL COMMUNICATIONS (2011)

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Article Polymer Science

Photodegradable, Photoadaptable Hydrogels via Radical-Mediated Disulfide Fragmentation Reaction

Benjamin D. Fairbanks et al.

MACROMOLECULES (2011)

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Review Multidisciplinary Sciences

Cancer immunotherapy comes of age

Ira Mellman et al.

NATURE (2011)

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Article Multidisciplinary Sciences

Reduced Neutrophil Apoptosis in Diabetic Mice during Staphylococcal Infection Leads to Prolonged Tnfα Production and Reduced Neutrophil Clearance

Frank Hanses et al.

PLOS ONE (2011)

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Article Multidisciplinary Sciences

Phagocytic Activity Is Impaired in Type 2 Diabetes Mellitus and Increases after Metabolic Improvement

Albert Lecube et al.

PLOS ONE (2011)

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Article Chemistry, Multidisciplinary

Three-Dimensional Self-Assembly of Graphene Oxide and DNA into Multifunctional Hydrogels

Yuxi Xu et al.

ACS NANO (2010)

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Article Multidisciplinary Sciences

Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice

Savita Khanna et al.

PLOS ONE (2010)

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Article Nanoscience & Nanotechnology

Click Chemistry in Tailor-Made Polymethacrylates Bearing Reactive Furfuryl Functionality: A New Class of Self-Healing Polymeric Material

A. Amalin Kavitha et al.

ACS APPLIED MATERIALS & INTERFACES (2009)

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Article Engineering, Biomedical

On the mechanisms of biocompatibility

David F. Williams

BIOMATERIALS (2008)

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Article Polymer Science

Preparation of hydrophobic association polyacrylamide in a new micellar copolymerization system and its hydrophobically associative property

Baojiao Gao et al.

MACROMOLECULES (2008)

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AMERICAN JOURNAL OF PATHOLOGY (2005)

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Article Dermatology

Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse:: Prolonged persistence of neutrophils and macrophages during the late phase of repair

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JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)

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Article Cell & Tissue Engineering

In vitro culture characteristics of corneal epithelial, endothelial, and keratocyte cells in a native collagen matrix

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