Related references
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Article
Engineering, Environmental
Elora Fournier et al.
Summary: This study investigated the impact of repeated exposure to polyethylene (PE) microplastics (MPs) on the human gut microbiota and intestinal barrier. The results showed that exposure to PE MPs caused donor-dependent effects, with a decrease in beneficial bacteria and an increase in potential pathogens. These bacterial shifts were associated with changes in volatile organic compound profiles. However, the impact of PE MPs on the intestinal barrier was not significant.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
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Walison Augusto da Silva Brito et al.
Summary: The ubiquity of microplastic particles has become a growing concern due to their impact on the environment, ecosystems, and potentially human health. This study investigated the effects of different polymer types, sizes, and concentrations of microplastics on human cell lines. The results showed that uptake of microplastics correlated with concentration and, for certain types of plastic, size. Interestingly, the effects on cellular metabolic activity and viability were minimal, but intracellular thiol content and cytokine secretion were significantly affected. This study highlights the importance of considering microplastic parameters in assessing their biological effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
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Yanliang Wu et al.
Summary: Nanoplastics pose potential respiratory toxicity by activating inflammatory responses in lung tissue. The NLRP3/caspase-1/IL-1 beta signaling pathway is implicated in the early inflammatory responses. The clinical antioxidant NAC shows promise in preventing and treating nanoplastics-induced pulmonary toxicity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Wiwik Bauten et al.
Summary: Researchers developed a multiplexed analytical and flow cytometry-based high-throughput method to quantify microplastic particles in aqueous suspensions, providing a sensitive and high-throughput detection capability.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Engineering, Environmental
Jinyuan Hu et al.
Summary: This review summarizes the physicochemical characteristics of microplastics (MPs) undergoing natural and artificial aging and evaluates current analytical methods used in aging studies. It discusses the differences in photoaging and aging induced by advanced oxidation processes (AOPs) and highlights the environmental behavior and adsorption properties of aged MPs. The mechanisms of photoaging and AOPs-initiated aging are also analyzed, along with the applications of 2D-COS and EEM-PARAFAC for aging process analysis.
Article
Chemistry, Applied
Cristina Di Fiore et al.
Summary: Sea salts collected from Italian salterns were solubilized in water and filtered to extract microplastics. Microplastics were quantified and classified based on their size and physical characteristics using microscopy. The most common types of polymers in these microplastics were identified using spectroscopy. The presence of a significant amount of microplastics in sea salt, with 80.6% having a fiber shape, has been revealed. This research is of global relevance due to the significant export of Italian salt.
Article
Engineering, Environmental
Ke Meng et al.
Summary: In this study, the potential of Lumbricus terrestris (earthworms) to reduce microplastic contamination in soils was explored. The experiment involved earthworms ingesting microplastics-contaminated soil and pure microplastics in the Petri Dish. The results showed that earthworms could survive in the microplastics-contaminated soil, indicating that soil facilitated the degradation of microplastics. Furthermore, the ingestion of microplastics by earthworms resulted in the fragmentation and depolymerization of certain polymers. Further research is needed to understand the mechanisms of polymer depolymerization in the earthworm gut and the feasibility of microplastic bioremediation with earthworms.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Abdullah Al Mamun et al.
Summary: While plastic has brought significant benefits to our lives, the issue of plastic particles in the environment has raised concerns. Plastics are resistant to degradation and can persist in the environment for a long time, leading to the entry of microplastics into the human food chain. Microplastic exposure through various sources can have negative impacts on human health, including gastrointestinal disorders, respiratory problems, and even cancer. It is important to regulate plastic use and ensure food safety to minimize the risks posed by microplastics. Future research should focus on understanding the composition of microplastics, their presence in different foods, and their biological effects on the human body.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Environmental Sciences
Md. Iftakharul Muhib et al.
Summary: Nowadays, microplastic contamination has been found in various environmental samples, but there have been few recent studies focusing on microplastic contamination in drinking sources and food packages. This review paper briefly summarizes the findings related to microplastic contamination in plastic drinking bottles, tap water, and food packaging containers. The literature shows that different types of microplastic fragments, such as polypropylene, polystyrene, polyethylene terephthalate, polyvinyl chloride, polyethylene, high-density polyethylene, low-density polyethylene, etc., have been detected. Microplastic fragmentation can be caused by mechanical stress, UV radiation, low quality plastic materials, aging, and atmospheric deposition. In addition, microplastics can accumulate various chemical compounds and complex materials from the surroundings, making their accurate detection challenging. The repeated usage of plastic drinking bottles and food containers at the community level can also lead to microplastic leaching and potential health risks. This narrative study highlights the need for more high-quality research in this field to better understand potential exposure to microplastics.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Lin Duan et al.
Summary: Microplastics in the environments can undergo aging processes that change their physicochemical properties and affect their affinity for contaminants. This study compares the effects of sulfide-induced aging and UV-induced aging on the binding of polypropylene, polystyrene, and polyethylene terephthalate microplastics to different contaminants. The two aging processes have different effects on the adsorption of specific contaminants by modifying the hydrophobicity, surface charges, and polarity of the microplastics. Understanding the environmental aging processes of microplastics is crucial, especially in anoxic environments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
M. Dilara Hatinoglu et al.
Summary: Microplastics (MPs) can carry organic pollutants such as per- and polyfluoroalkyl substances (PFAS). Therefore, it is important to understand the adsorptive interactions between MPs and PFAS in natural waters. This study developed a predictive model for the adsorption of PFAS by MPs using a subset of ionizable perfluoroalkyl carboxylic acids (PFCA) and provided insights into the factors affecting their adsorption. The results showed that the polarizability and hydrophobicity of anionic PFCA were the most significant contributors to their adsorption by MPs, while van der Waals interactions between PFCA and water decreased their binding affinity. Overall, the study demonstrated the potential of linear solvation energy relationships (LSER) for predicting the adsorption of ionizable PFAS by MPs after accounting for their ionization.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Xiuna Ren et al.
Summary: This study investigates the characteristics and mechanisms of dissolved organic carbon (DOC) and nano-plastics (NPs) released from microplastics (MPs) under different aging conditions. The results show that aging reduces the abundance of MPs, and high temperature and UV aging generate smaller-sized MPs. The release of DOC is related to the type and aging condition of MPs. Additionally, a significant amount of NPs is detected in leachates from PVC and PS MPs-aged treatments, with high temperature and UV promoting their release.
Article
Chemistry, Multidisciplinary
Juan Tang et al.
Summary: Exposure to nanoplastics during pregnancy resulted in small intestinal injury in the offspring, with female mice showing a greater decrease in birth weight but higher adult body weights. Histological changes and upregulation of reactive oxygen species were observed in the small intestines of both female and male offspring. Sex-specific differences in gene expression levels were also observed. These findings indicate that PS-NP exposure during pregnancy can cause sex-specific small intestinal toxicity, potentially through reactive oxygen species activation and subsequent ferroptosis.
Article
Environmental Sciences
Yuheng Zhong et al.
Summary: In this study, the influence of UV aging on the adsorption of organic pollutants by mPVC and the toxicity variations among different types of mPVCs to zebrafish were investigated. UV irradiation significantly changed the physiochemical properties of mPVC, resulting in more oxygen-containing groups and free radicals on the surfaces. Aging reduced the adsorption of mPVC against a hydrophobic compound but enhanced the adsorption against a moderately hydrophilic compound. Ingestion of pollutant-loaded mPVCs led to bioaccumulation in zebrafish and caused severer gut damages and oxidative stresses. The study highlights the need for using environmentally relevant mPVCs in toxicity studies of MPs.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Wei Song et al.
Summary: In this study, the single and combined toxicity of microplastics (MPs) and organic pollutants on Chlorella pyrenoidosa were investigated. The results showed that the combined impact of UV-aged MPs and organic pollutants had a significant damaging effect on algae cells. This research verified the remarkable combined toxicity between UV-aged MPs and organic pollutants on microalgae.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Madushika Sewwandi et al.
Summary: Microplastics have become a global concern due to their ubiquitous presence and the unavoidable human exposure risks they pose. However, there is a lack of overall understanding regarding the presence of microplastics and plastics-associated contaminants in food and beverages. This article attempts to review the geographical distribution of studies on microplastics and plastics-associated contaminants in food and beverages, as well as the ingestion potency of micropollutants and the possible health impacts. The review highlights the urgent need for more investigations in order to better assess potential human exposure and health risks.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Lixin Wang et al.
Summary: Microplastics (MPs) are a newly emerging type of pollutants that have been found in various environments, including the atmosphere, soil, water, and even human samples. The co-existence of multiple heavy metals with MPs raises concerns about their combined toxicity. This study investigated the toxic effects of polystyrene MPs (PS-MPs) and cadmium chloride (CdCl2) on the liver and hepatocytes. The findings revealed that PS-MPs alone or combined with CdCl2 induced a form of programmed cell death called ferroptosis in hepatocytes, which was characterized by lipid oxidation and iron accumulation. The ferroptotic effect was enhanced by ROS production and inhibited antioxidant activity, but could be rescued by specific inhibitors.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Peng Liu et al.
Summary: The study revealed the impact of aged MPs on the bioaccumulation of pharmaceuticals in marine organisms, and highlighted the combined risks of aged MPs and pharmaceuticals in the environment.
Article
Environmental Sciences
Xingli Zhang et al.
Summary: The study reveals that environmentally aged microplastics can potentially negatively impact diet digestion and nutrient assimilation in fish, leading to intestinal issues and growth inhibition.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Engineering, Environmental
Zehua Yan et al.
Summary: The study found that the concentration of fecal microplastics in patients with inflammatory bowel disease was significantly higher than in healthy individuals, with poly(ethylene terephthalate) and polyamide being the main components in the feces. A positive correlation between fecal microplastics concentration and the severity of IBD was also observed. Plastic packaging of drinking water and food, as well as dust exposure, were identified as important sources of human exposure to microplastics.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Yaru Li et al.
Summary: A tailored Trojan horse nanocarrier with pH-labile zeolitic imidazolate framework-8 (ZIF-8) as the core and disulfide-linked amphiphilic polymer-drug conjugate as the steric shell is designed. The nanocarrier exhibits improved drug release and therapeutic efficacy through the collapse of ZIF-8 under low pH conditions, inducing the liberation and further cleavage of the drug.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Environmental Sciences
Yingwen Mu et al.
Summary: The study shows that microplastics can damage the liver structure and function in mice, leading to inflammation and oxidative damage, and triggering processes of pyroptosis and ferroptosis.
Article
Environmental Sciences
Wei Cheng et al.
Summary: This study investigated the adverse biological effects of microplastic particles on human liver using a novel in vitro 3D model, revealing potential hepatotoxicity and disruption of lipid metabolism. The findings provide insights into the risks associated with microplastics on human health.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Environmental
Lujian Lin et al.
Summary: This study investigates the role of disposable face masks (DFMs) as vectors of metal ions in the environment. Aging process promotes metal ion adsorption onto DFMs, mainly due to the presence of oxygen-containing groups. Pristine and aged DFMs have higher adsorption affinity for metal ions with greater electronegativity. Environmental factors like salinity and solution pH affect the adsorption capacity of DFMs. Overall, this study provides insights into the environmental behaviors and risks of DFMs associated with metals.
CHEMICAL ENGINEERING JOURNAL
(2022)
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Engineering, Environmental
Sindoval Silva de Souza et al.
Summary: In recent years, there has been an increasing number of studies on the impact of microplastics on biota. However, the effects of microplastics on birds' health are not well understood. This study aimed to evaluate the effects of ingestion of naturally-aged microplastics by Coturnix Coturnix japonica and found that ingested microplastics led to a reduction in body biomass and various biochemical alterations associated with oxidative stress, redox imbalance, and cholinesterasic effects in birds.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Yujiao He et al.
Summary: The widespread occurrence of nanoplastics has become a global threat to animals and human health. This study explores the impact of polystyrene nanoparticles (PSNPs) on the intestinal barrier and inflammation, and identifies the molecular mechanism involving the ROS drived-NF-kappa B/NLRP3 pathway.
Article
Environmental Sciences
Peng Zhang et al.
Summary: In this study, the size effects of aged microplastics (AMPs) on the uptake, elimination, tissue distribution, and potential toxicity of roxithromycin (ROX) in Carassius auratus were investigated. The results showed that AMPs promoted the accumulation of ROX in various tissues, and exacerbated the pathological abnormalities induced by ROX. High-throughput sequencing and metabolomics revealed the impact of AMPs and ROX on gut microbiota and metabolites.
ENVIRONMENT INTERNATIONAL
(2022)
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Engineering, Environmental
Ruiqi Bao et al.
Summary: Biodegradable plastics release a large amount of secondary microplastics during long-term UV aging, and the formation of biofilms on their surfaces is also observed. These microplastics exhibit high levels of abundance and genes related to human pathogens and diseases are detected on their surfaces.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Pengfei Wu et al.
Summary: This article provides an overview of the presence and potential health impacts of microplastics in the biosphere, with a focus on inhalation and ingestion as the major exposure pathways. It discusses the absorption, distribution, metabolic toxicity, and excretion of microplastics in the human body, as well as the potential risks associated with them.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Gastroenterology & Hepatology
Tadahiro Shinozawa et al.
Summary: This study established a screening model based on human liver organoids (HLO) for analyzing drug-induced liver injury (DILI) pathology, providing unique advantages at the organoid resolution. Through this model, a multi-readout organoid analysis was successfully developed to measure viability, cholestatic and/or mitochondrial toxicity, showing high predictive values for marketed drugs.
Article
Biochemical Research Methods
Michael T. Sturm et al.
Summary: In recent years, there has been extensive research on developing a cost-effective and easily applicable method for detecting microplastics using Nile red and its derivatives. Additionally, the influence of different solvents and water pH values on the dyeing process was investigated by analyzing fluorescence spectra. The developed method was also tested on sea salt samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Xin Chen et al.
Summary: Ferroptosis is an iron-dependent oxidative cell death driven by lipid peroxidation. Various antioxidant systems play a significant role in preventing ferroptotic death. The cellular degradation systems play a dual role in regulating the ferroptotic response.
CELL DEATH AND DIFFERENTIATION
(2021)
Review
Chemistry, Multidisciplinary
Ellen Fritsche et al.
Summary: The call for a paradigm change in toxicology initiated by the United States National Research Council in 2007 highlights the importance of human-relevant alternative methods for toxicological hazard assessment. This review article discusses critical organs such as skin, brain, and lungs in terms of their functions in health and disease, emphasizing the need for more complex organotypic models. Innovative technologies like organs-on-a-chip and genome editing are paving the way for a shift in toxicological paradigm towards more advanced and human-specific approaches.
Article
Environmental Sciences
Minwei Xie et al.
Summary: Research has shown that aged microplastics in the environment accumulate metals, with a different behavior compared to metals adsorbed on new plastics in laboratory settings. This highlights the complexity of metal accumulation behavior in the real environment and suggests caution when translating laboratory findings to risk assessment of metal contaminated microplastics.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Monica Fabra et al.
Summary: The study found that uptake of E. coli coated microplastics was significantly higher than that of virgin microplastics in European native oysters, with oysters exposed to coated microplastics also showing increased oxygen consumption and respiration rate over time compared to those exposed to virgin microplastics. Despite microplastics not bioaccumulating in oyster tissues in the short-term, microorganisms assimilated by ingestion of coated microplastics may be transferred to higher trophic levels, posing a risk to wildlife, food safety, and human health. Microplastics have the potential to act as vectors for disease by carrying pathogens and exposing a wide range of organisms to them.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Su-chun Wang et al.
Summary: The study found that the effects of polystyrene (PS) and triphenyl phosphate (TPhP) on Chaetoceros meulleri showed a certain level of antagonism, but high concentrations of PS and TPhP still caused noticeable damage to the cell membranes of the algae.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Multidisciplinary
Jingyi Guo et al.
Summary: The study reprogrammed skin fibroblasts from two patients into induced pluripotent stem cells (iPSCs) and corrected them using CRISPR/Cas9, generating high purity hepatocyte organoids and hepatocyte-like cells as cellular models. It revealed that DGUOK mutant hepatocytes are more sensitive to iron overload-induced ferroptosis, and this process can be rescued by N-Acetylcysteine (NAC).
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Alison Bain et al.
Summary: Research shows the presence and long-range transport of microplastics in the atmosphere, but the interactions between these microplastics and atmospheric aerosol are not fully understood. Environmental microplastics, with variations in color, morphology, and chemical composition, can become oxidized over time. It is found that UV-aged plastics exhibit higher water sorption than pristine plastics, indicating a potential impact on atmospheric water uptake.
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Fabrice Laine et al.
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Pharmacology & Pharmacy
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
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