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Nanotechnology-Based Drug Delivery Systems for Honokiol: Enhancing Therapeutic Potential and Limitations

INTERNATIONAL JOURNAL OF NANOMEDICINE (2023)

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Safety and Toxicology of Magnolol and Honokiol

Andrea Sarrica et al.

PLANTA MEDICA (2018)

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Article Cell Biology

Honokiol is a FOXM1 antagonist

Marianna Halasi et al.

CELL DEATH & DISEASE (2018)

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Article Biotechnology & Applied Microbiology

Oligochitosan-pluronic 127 conjugate for delivery of honokiol

Zhimei Song et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

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Article Pharmacology & Pharmacy

Development of a Chitosan-based Nanoparticle Formulation for Ophthalmic Delivery of Honokiol

Feng Deng et al.

CURRENT DRUG DELIVERY (2018)

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Review Medicine, Research & Experimental

Honokiol: An anticancer lignan

Abdur Rauf et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

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Article Chemistry, Medicinal

A novel honokiol liposome: formulation, pharmacokinetics, and antitumor studies

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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2018)

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Review Chemistry, Medicinal

Redox-responsive nano-carriers as tumor-targeted drug delivery systems

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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

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Review Pharmacology & Pharmacy

Vesicular systems employing natural substances as promising drug candidates for MMP inhibition in glioblastoma: A nanotechnological approach

Srishti Agarwal et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Chemistry, Multidisciplinary

Pluronic F127-cyclodextrin conjugate micelles for encapsulation of honokiol

Runliang Feng et al.

JOURNAL OF NANOPARTICLE RESEARCH (2018)

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Article Biotechnology & Applied Microbiology

Functional paclitaxel plus honokiol micelles destroying tumour metastasis in treatment of non-small-cell lung cancer

Xin Wang et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

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Article Biotechnology & Applied Microbiology

Lactoferrin-tagged quantum dots-based theranostic nanocapsules for combined COX-2 inhibitor/herbal therapy of breast cancer

Ahmed S. AbdElhamid et al.

NANOMEDICINE (2018)

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Article Pharmacology & Pharmacy

Antitumor efficacy of Lf modified daunorubicin plus honokiol liposomes in treatment of brain glioma

Shuang Liu et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)

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Article Materials Science, Biomaterials

Honokiol nanoparticles stabilized by oligoethylene glycols codendrimer: in vitro and in vivo investigations

Yifei Guo et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

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Article Multidisciplinary Sciences

Enhancing the anti-glioma therapy of doxorubicin by honokiol with biodegradable self-assembling micelles through multiple evaluations

Xiang Gao et al.

SCIENTIFIC REPORTS (2017)

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Article Engineering, Biomedical

Concurrently suppressing multidrug resistance and metastasis of breast cancer by co-delivery of paclitaxel and honokiol with pH-sensitive polymeric micelles

Ziqi Wang et al.

ACTA BIOMATERIALIA (2017)

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Review Chemistry, Multidisciplinary

Ligand-Targeted Drug Delivery

Madduri Srinivasarao et al.

CHEMICAL REVIEWS (2017)

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Article Engineering, Biomedical

Liposomal honokiol induced lysosomal degradation of Hsp90 client proteins and protective autophagy in both gefitinib-sensitive and gefitinib-resistant NSCLC cells

Jianhong Yang et al.

BIOMATERIALS (2017)

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Article Biophysics

Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC)

Chandraiah Godugu et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

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Article Pharmacology & Pharmacy

Honokiol-loaded polymeric nanoparticles: an active targeting drug delivery system for the treatment of nasopharyngeal carcinoma

Bo Yang et al.

DRUG DELIVERY (2017)

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Article Pharmacology & Pharmacy

Co-delivery of honokiol, a constituent of Magnolia species, in a self-microemulsifying drug delivery system for improved oral transport of lipophilic sirolimus

Weiming Ding et al.

DRUG DELIVERY (2016)

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Article Chemistry, Multidisciplinary

Preparation of honokiol with biodegradable nanoparticles for treatment of osteosarcoma

Yongzhong Cheng et al.

RSC ADVANCES (2016)

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Article Chemistry, Applied

Encapsulation of honokiol into self-assembled pectin nanoparticles for drug delivery to HepG2 cells

Yuxia Zhang et al.

CARBOHYDRATE POLYMERS (2015)

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Article Pharmacology & Pharmacy

Sirolimus-loaded polymeric micelles with honokiol for oral delivery

Xinru Li et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2015)

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Article Biophysics

Honokiol nanosuspensions: Preparation, increased oral bioavailability and dramatically enhanced biodistribution in the cardio-cerebro-vascular system

Meihua Han et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2014)

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Article Plant Sciences

UPLC-MS/MS-ESI assay for simultaneous determination of magnolol and honokiol in rat plasma: Application to pharmacokinetic study after administration emulsion of the isomer

Yi-Ling Sheng et al.

JOURNAL OF ETHNOPHARMACOLOGY (2014)

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Review Medicine, Research & Experimental

Honokiol: A Novel Natural Agent for Cancer Prevention and Therapy

S. Arora et al.

CURRENT MOLECULAR MEDICINE (2012)

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Article Chemistry, Multidisciplinary

Improving therapeutic effect in ovarian peritoneal carcinomatosis with honokiol nanoparticles in a thermosensitive hydrogel composite

Yao Xie et al.

RSC ADVANCES (2012)

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Article Pharmacology & Pharmacy

Improved solubility and pharmacokinetics of PEGylated liposomal honokiol and human plasma protein binding ability of honokiol

Xian-Huo Wang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)

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Article Chemistry, Medicinal

Preparation, Characterization, Pharmacokinetics, and Bioactivity of Honokiol-in-Hydroxypropyl-β-Cyclodextrin-in-Liposome

Xianhuo Wang et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2011)

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Article Oncology

Synergistic antitumor effects of liposomal honokiol combined with cisplatin in colon cancer models

Niang Cheng et al.

ONCOLOGY LETTERS (2011)

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Synthesis, structural and in vitro studies of well-dispersed monomethoxy-poly(ethylene glycol)-honokiol conjugate micelles

Neng Qiu et al.

BIOMEDICAL MATERIALS (2010)

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Article Chemistry, Physical

Self-assembled biodegradable micelles based on star-shaped PCL-b-PEG copolymers for chemotherapeutic drug delivery

PengWei Dong et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2010)

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Article Pharmacology & Pharmacy

A novel transdermal honokiol formulation based on Pluronic F127 copolymer

XiuLing Zheng et al.

DRUG DELIVERY (2010)

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Preparation of MPEG-PLA nanoparticle for honokiol delivery in vitro

XiuLing Zheng et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2010)

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Article Engineering, Biomedical

Polymeric matrix for drug delivery: Honokiol-loaded PCL-PEG-PCL nanoparticles in PEG-PCL-PEG thermosensitive hydrogel

MaLing Gou et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2010)

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Article Pharmacology & Pharmacy

Development of nanosomes using high-pressure homogenization for gene therapy

Anup K. Kundu et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2010)

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Article Nanoscience & Nanotechnology

Biodegradable self-assembled PEG-PCL-PEG micelles for hydrophobic honokiol delivery: I. Preparation and characterization

ChangYang Gong et al.

NANOTECHNOLOGY (2010)

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Article Chemistry, Multidisciplinary

Honokiol Nanoparticles in Thermosensitive Hydrogel: Therapeutic Effects on Malignant Pleural Effusion

Fang Fang et al.

ACS NANO (2009)

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Article Biotechnology & Applied Microbiology

In vitro drug release behavior from a novel thermosensitive composite hydrogel based on Pluronic f127 and poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) copolymer

Chang Yang Gong et al.

BMC BIOTECHNOLOGY (2009)

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Article Oncology

Liposomal honokiol inhibits VEGF-D-induced lymphangiogenesis and metastasis in xenograft tumor model

Jing Wen et al.

INTERNATIONAL JOURNAL OF CANCER (2009)

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Article Pharmacology & Pharmacy

Self-assembled honokiol-loaded micelles based on poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) copolymer

XiaWei Wei et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)

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Article Pharmacology & Pharmacy

Poly(ε-caprolactone)-poly(ethylene glycol) -poly(ε-caprolactone) (PCL-PEG-PCL) nanoparticles for honokiol delivery in vitro

MaLing Gou et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)

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Article Chemistry, Physical

Novel Composite Drug Delivery System for Honokiol Delivery: Self-Assembled Poly(ethylene glycol)-Poly(ε-caprolactone)-Poly(ethylene glycol) Micelles in Thermosensitive Poly(ethylene glycol)-Poly(ε-caprolactone)-Poly(ethylene glycol) Hydrogel

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JOURNAL OF PHYSICAL CHEMISTRY B (2009)

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Article Chemistry, Multidisciplinary

Self-Assembled Hydrophobic Honokiol Loaded MPEG-PCL Diblock Copolymer Micelles

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PHARMACEUTICAL RESEARCH (2009)

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Article Oncology

Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer model

Qi-qi Jiang et al.

BMC CANCER (2008)

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Article Oncology

Enhancement of therapeutic effectiveness by combining liposomal honokiol with cisplatin in ovarian carcinoma

Y. Liu et al.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2008)

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A novel injectable local hydrophobic drug delivery system: Biodegradable nanoparticles in thermo-sensitive hydrogel

MaLing Gou et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)

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Article Oncology

Liposomal honokiol, a promising agent for treatment of cisplatin-resistant human ovarian cancer

Hong Luo et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2008)

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Article Engineering, Biomedical

Preparation and characterization of honokiol nanoparticles

Ma Ling Gou et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2008)

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Article Chemistry, Medicinal

Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models

Wenli Hou et al.

PHYTOTHERAPY RESEARCH (2008)

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Article Oncology

Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol

Dong Xu et al.

CANCER LETTERS (2006)

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