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Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents

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Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K/Akt signaling pathway

Yanlong Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

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Article Biochemistry & Molecular Biology

Polysaccharide with antioxidant, α-amylase inhibitory and ACE inhibitory activities from Momordica charantia

Hwee-Feng Tan et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

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Review Immunology

Replicative capacity of β-cells and type 1 diabetes

Diane Saunders et al.

JOURNAL OF AUTOIMMUNITY (2016)

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Article Endocrinology & Metabolism

Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population

Carmen Haro et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

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Article Nutrition & Dietetics

Effects of whole-grain cereal foods on plasma short chain fatty acid concentrations in individuals with the metabolic syndrome

Claudia Vetrani et al.

NUTRITION (2016)

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Article Multidisciplinary Sciences

Effects of Arabinoxylan and Resistant Starch on Intestinal Microbiota and Short-Chain Fatty Acids in Subjects with Metabolic Syndrome: A Randomised Crossover Study

Stine Hald et al.

PLOS ONE (2016)

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Article Multidisciplinary Sciences

Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

Stephanie R. Villa et al.

SCIENTIFIC REPORTS (2016)

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Article Medicine, General & Internal

Sulfonylureas and their use in clinical practice

Daniele Sola et al.

ARCHIVES OF MEDICAL SCIENCE (2015)

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Article Nutrition & Dietetics

Increased gut hormones and insulin sensitivity index following a 3-d intervention with a barley kernel-based product: a randomised cross-over study in healthy middle-aged subjects

Anne C. Nilsson et al.

BRITISH JOURNAL OF NUTRITION (2015)

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Article Endocrinology & Metabolism

GPR43 Potentiates β-Cell Function in Obesity

Joanne C. McNelis et al.

DIABETES (2015)

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Article Pharmacology & Pharmacy

Coumaglutide, a novel long-acting GLP-1 analog, inhibits β-cell apoptosis in vitro and invokes sustained glycemic control in vivo

Lidan Sun et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2015)

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Article Endocrinology & Metabolism

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

Medha Priyadarshini et al.

MOLECULAR ENDOCRINOLOGY (2015)

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Review Endocrinology & Metabolism

Short-chain fatty acids in control of body weight and insulin sensitivity

Emanuel E. Canfora et al.

NATURE REVIEWS ENDOCRINOLOGY (2015)

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Review Endocrinology & Metabolism

Study of Protein Biomarkers of Diabetes Mellitus Type 2 and Therapy with Vitamin B1

Samreen Riaz

JOURNAL OF DIABETES RESEARCH (2015)

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Article Gastroenterology & Hepatology

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

Edward S. Chambers et al.

GUT (2015)

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Review Plant Sciences

Medicinal plants contain mucilage used in traditional Persian medicine (TPM)

Ahmad Ameri et al.

PHARMACEUTICAL BIOLOGY (2015)

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Article Multidisciplinary Sciences

Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor. and Glucagon-Like Peptide-1

Gijs den Besten et al.

PLOS ONE (2015)

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Article Chemistry, Applied

Chemical and antihyperglycemic activity changes of ginseng pectin induced by heat processing

Lili Jiao et al.

CARBOHYDRATE POLYMERS (2014)

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Article Food Science & Technology

Compositional, spectroscopic and rheological analyses of mucilage isolated from taro (Colocasia esculenta L. Schott) corms

Nicolas Yanou Njintang et al.

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2014)

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Article Food Science & Technology

Hypoglycemic and hypolipidemic effect of Aloe vera L. in non-insulin dependent diabetics

Monika Choudhary et al.

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2014)

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Review Cell Biology

Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes

Alessandra Puddu et al.

MEDIATORS OF INFLAMMATION (2014)

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Review Integrative & Complementary Medicine

Clinical and experimental studies on polyherbal formulations for diabetes: current status and future prospective

Ahmad Ghorbani

JOURNAL OF INTEGRATIVE MEDICINE-JIM (2014)

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Article Chemistry, Multidisciplinary

Comparative Analysis of in vitro Antioxidant Activity of Two Selected Plants With a Reference to Antidiabetic Profile

Dilipkumar Pal

ASIAN JOURNAL OF CHEMISTRY (2013)

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Article Nutrition & Dietetics

Improvement of the metabolic syndrome profile by soluble fibre - guar gum - in patients with type 2 diabetes: a randomised clinical trial

Valesca Dall'Alba et al.

BRITISH JOURNAL OF NUTRITION (2013)

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Review Endocrinology & Metabolism

GLP-1 receptor activated insulin secretion from pancreatic ss-cells: mechanism and glucose dependence

A. R. Meloni et al.

DIABETES OBESITY & METABOLISM (2013)

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Article Biochemistry & Molecular Biology

α-D-Glucosidase inhibitory activity of polysaccharide isolated from Acacia tortilis gum exudate

Swati Bisht et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2013)

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Article Multidisciplinary Sciences

Gut metagenome in European women with normal, impaired and diabetic glucose control

Fredrik H. Karlsson et al.

NATURE (2013)

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Article Multidisciplinary Sciences

Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance

Xiuying Zhang et al.

PLOS ONE (2013)

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Article Endocrinology & Metabolism

Effects of High Performance Inulin Supplementation on Glycemic Control and Antioxidant Status in Women with Type 2 Diabetes

Bahram Pourghassem Gargari et al.

DIABETES & METABOLISM JOURNAL (2013)

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Article Endocrinology & Metabolism

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

Gwen Tolhurst et al.

DIABETES (2012)

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Article Chemistry, Applied

In vitro retardation of glucose diffusion with gum extracted from malva nut seeds produced in Thailand

Anchalee Srichamroen et al.

FOOD CHEMISTRY (2011)

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Article Agriculture, Multidisciplinary

Inhibitory Effects of Dioscorea Polysaccharide on TNF-α-Induced Insulin Resistance in Mouse FL83B Cells

Bao-Hong Lee et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)

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Article Plant Sciences

In vitro and in vivo acute antihyperglycemic effects of five selected indigenous plants from Jordan used in traditional medicine

Violet Kasabri et al.

JOURNAL OF ETHNOPHARMACOLOGY (2011)

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Article Food Science & Technology

In vitro hypoglycemic effects of selected dietary fiber sources

Faiyaz Ahmed et al.

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE (2011)

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Article Chemistry, Medicinal

Pectin from Passiflora edulis Shows Anti-inflammatory Action as well as Hypoglycemic and Hypotriglyceridemic Properties in Diabetic Rats

Draulio C. Silva et al.

JOURNAL OF MEDICINAL FOOD (2011)

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Article Biochemistry & Molecular Biology

Effect of cellulose, pectin and chromium(III) on lipid and carbohydrate metabolism in rats

Monika Krzysik et al.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2011)

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Review Biochemistry & Molecular Biology

Chemistry, physico-chemistry and applications linked to biological activities of beta-glucans

Laura Barsanti et al.

NATURAL PRODUCT REPORTS (2011)

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Article Nutrition & Dietetics

Factors related to colonic fermentation of nondigestible carbohydrates of a previous evening meal increase tissue glucose uptake and moderate glucose-associated inflammation

Marion G. Priebe et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)

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Article Nutrition & Dietetics

Prebiotic effects: metabolic and health benefits

Marcel Roberfroid et al.

BRITISH JOURNAL OF NUTRITION (2010)

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Review Chemistry, Medicinal

Anti-Diabetic Agents from Natural Products-An Update from 2004 to 2009

Lian-Wen Qi et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2010)

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Nitrogen efficiency of wheat: Genotypic and environmental variation and prospects for improvement

Peter B. Barraclough et al.

EUROPEAN JOURNAL OF AGRONOMY (2010)

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Diabetes area participation analysis: a review of companies and targets described in the 2008-2010 patent literature

Philip A. Carpino et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2010)

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Article Food Science & Technology

Antihyperglycemic and antihyperlipidemic activities of methanol:water (4:1) fraction isolated from aqueous extract of Syzygium alternifolium seeds in streptozotocin induced diabetic rats

Ramesh Babu Kasetti et al.

FOOD AND CHEMICAL TOXICOLOGY (2010)

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Review Nutrition & Dietetics

Effects of Dietary Fiber and Its Components on Metabolic Health

James M. Lattimer et al.

NUTRIENTS (2010)

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Article Nutrition & Dietetics

Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults

Jill A. Parnell et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)

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Article Nutrition & Dietetics

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

Patrice D. Cani et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)

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Review Endocrinology & Metabolism

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

Ralph A. DeFronzo

DIABETES (2009)

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Article Food Science & Technology

Effect of flaxseed gum on reduction of blood glucose and cholesterol in type 2 diabetic patients

Goutam Thakur et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2009)

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Article Plant Sciences

Antidiabetic effects of Artemisia sphaerocephala Krasch gum, a novel food additive in China, on streptozotocin-induced type 2 diabetic rats

Xiao-Hui Xing et al.

JOURNAL OF ETHNOPHARMACOLOGY (2009)

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Article Integrative & Complementary Medicine

Hypoglycemic herbs and their action mechanisms

Hongxiang Hui et al.

Chinese Medicine (2009)

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GLP-1 receptor signaling:: effects on pancreatic β-cell proliferation and survival

J. Buteau

DIABETES & METABOLISM (2008)

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Article Chemistry, Applied

The effect of steaming on the free amino acid contents and antioxidant activity of Panax ginseng

Eun Jung Cho et al.

FOOD CHEMISTRY (2008)

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Article Nutrition & Dietetics

Metabolic effects of dietary and prevention of diabetes

Martin O. Weickert et al.

JOURNAL OF NUTRITION (2008)

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Novel rhamnogalacturonan I and arabinoxylan polysaccharides of flax seed mucilage

Radnaa Naran et al.

PLANT PHYSIOLOGY (2008)

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Article Nutrition & Dietetics

Prebiotic capacity of inulin-type fructans

Sofia Kolida et al.

JOURNAL OF NUTRITION (2007)

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Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: Experimental data

Nathalie M. Delzenne et al.

JOURNAL OF NUTRITION (2007)

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Article Food Science & Technology

Influence of pectin and guar gum composite flour on plasma biochemical profile of streptozotocin-induced diabetic male albino rats

M. S. Butt et al.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES (2007)

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Article Nutrition & Dietetics

Impact of sugar beet pectin and polydextrose on fasting and postprandial glycemia and fasting concentrations of serum total and lipoprotein lipids in middle-aged subjects with abnormal glucose metabolism

U. Schwab et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2006)

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Article Nutrition & Dietetics

Oligofructose promotes satiety in healthy human: a pilot study

PD Cani et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2006)

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Article Nutrition & Dietetics

Dietary fibers affect viscosity of solutions and simulated human gastric and small intestinal digesta

CL Dikeman et al.

JOURNAL OF NUTRITION (2006)

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Article Plant Sciences

Psyllium decreased serum glucose and glycosylated hemoglobin significantly in diabetic outpatients

SA Ziai et al.

JOURNAL OF ETHNOPHARMACOLOGY (2005)

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Article Nutrition & Dietetics

Antidiabetic property of fenugreek seed mucilage and spent turmeric in streptozotocin-induced diabetic rats

GS Kumar et al.

NUTRITION RESEARCH (2005)

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Comparison of expression of glucokinase gene and activities of enzymes related to glucose metabolism in livers between dog and cat

A Tanaka et al.

VETERINARY RESEARCH COMMUNICATIONS (2005)

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Article Plant Sciences

Modulatory effect of fenugreek seed mucilage and spent turmeric on intestinal and renal disaccharidases in streptozotocin induced diabetic rats

GS Kumar et al.

PLANT FOODS FOR HUMAN NUTRITION (2005)

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Article Endocrinology & Metabolism

Treatment of type 2 diabetes with a combination regimen of repaglinide plus pioglitazone

L Jovanovic et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2004)

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Article Biochemistry & Molecular Biology

The gel-forming polysaccharide of psyllium husk (Plantago ovata Forsk)

MH Fischer et al.

CARBOHYDRATE RESEARCH (2004)

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Article Food Science & Technology

Comparison of the characteristics, functional properties, and in vitro hypoglycemic effects of various carrot insoluble fiber-rich fractions

CF Chau et al.

LEBENSMITTEL-WISSENSCHAFT UND-TECHNOLOGIE-FOOD SCIENCE AND TECHNOLOGY (2004)

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Article Gastroenterology & Hepatology

Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease

T Piche et al.

GASTROENTEROLOGY (2003)

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Addition of inulin to a moderately high-carbohydrate diet reduces hepatic lipogenesis and plasma triacylglycerol concentrations in humans

D Letexier et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2003)

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Article Plant Sciences

Mucilages and polysaccharides in Ziziphus species (Rhamnaceae): localization, composition and physiological roles during drought-stress

SC Clifford et al.

JOURNAL OF EXPERIMENTAL BOTANY (2002)

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Article Nutrition & Dietetics

Acetic acid feeding enhances glycogen repletion in liver and skeletal muscle of rats

T Fushimi et al.

JOURNAL OF NUTRITION (2001)

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Article Endocrinology & Metabolism

Long-term dietary treatment with increased amounts at fiber-rich low-glycemic index natural foods improves blood glucose control and reduces the number of hypoglycemic events in type 1 diabetic patients

R Giacco et al.

DIABETES CARE (2000)

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