4.5 Article

Synthesis, characterization and in vitro biocompatibility assessment of a novel tripeptide hydrogelator, as a promising scaffold for tissue engineering applications

Journal

BIOMATERIALS SCIENCE
Volume 4, Issue 10, Pages 1412-1416

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6bm00287k

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Funding

  1. Ministry of Science, Education and Sports of the Republic of Croatia
  2. Croatian Science Foundation (HRZZ project) [IP-11-2013-7387]
  3. EU FP7 Glow-Brain project [REGPOT-2012-CT2012-316120]
  4. European Regional Development Fund (ERDF) - EU FP7 grant

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We have synthesized and characterized a self-assembling tripeptide hydrogelator Ac-L-Phe-L-Phe-L-Ala-NH2. A series of experiments showed that the hydrogel material could serve as a stabile and biocompatible physical support as it improves the survival of HEK293T cells in vitro, thus being a promising biomaterial for use in tissue engineering applications.

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