4.4 Article

The effects of fractional time derivatives in bioheat conduction technique on tumor thermal therapy

Journal

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/jnet-2023-0065

Keywords

cancer cells; Laplace transforms; fractional bioheat equation; hyperthermia

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This article utilizes the fractional bioheat model in spherical coordinates to explain the transfer of heat in living tissues during magnetic hyperthermia treatment for tumors. It proposes a hybrid numerical approach to accurately estimate power dissipation and investigates the impact of fractional parameter and differences in thermophysical properties between diseased and healthy tissue on temperature.
The article utilizes the fractional bioheat model in spherical coordinates to explain the transfer of heat in living tissues during magnetic hyperthermia treatment for tumors. Maintaining therapeutic temperature is crucial in magnetic fluid hyperthermia, which requires accurate estimations of power dissipation to determine the appropriate number of magnetic particles required for treatment. To address this problem, a hybrid numerical approach that combines Laplace transforms, change of variables, and modified discretization techniques is proposed in this paper. The study investigates the impact of the fractional parameter and differences in thermophysical properties between diseased and healthy tissue. The numerical temperature results are presented in a graph, and their validity is demonstrated by comparing them with previous literature.

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